上海市松江区中心医院2010--2012年住院药房抗生素使用情况分析

目的了解上海市松江区中心医院住院药房抗生素的使用情况，为临床合理用药提供参考。方法统计2010---2012年住院药房抗生素的消耗金额、用药总剂量、限定日剂量（DDD）、用药天数、用药频率（DDDS）、日均费用（DDC）、药物利用指数（DUI）以及抗生素使用率、抗生素使用强度（AUD）等，分析临床应用情况。结果3年来上海市松江区中心医院抗生素使用率和使用强度都超过了卫生部的相关标准，但呈现下降趋势。结论住院药房对抗生素的用药基本合理，但个别药物DUI〉1，存在不合理使用情况，应进一步加强对抗生素使用的监督管理，防止少数抗生素的滥用。

Analysis of clinical use of antibiotics from inpatient pharmacy in Songjiang Central Hospital of Shanghai in 2010 2012

Objective To analyze the clinical use of antibiotics from inpatient pharmacy in Songjiang Central Hospital of Shanghai, and to provide the evidence for clinically reasonable use of antibiotics. Methods By calculating the following parameters between 2010 and 2012, including the cOSt of antibiotics from inpatient pharmacy, total amount of antibiotics, defined daily dose （DDD）, duration of antibiotics use, DDDS, DDC, drug utilization index （DUI）, frequency of antibiotics use for each patient, antibiotics use density （AUD）, etc, the clinical use of antibiotics was analyzed. Results The frequency and amount of antibiotic used in the past 3 years were significantly larger than the requireinents of the standard of Ministry of Public Health; However, the trends of antibiotics use were decreased from 2010 to 2012. Conclusion： The antibiotics use from inpatient pharmacy remains unreasonable, and even the DUI for certain antibiotics is larger than 1. Therefore, the supervision of clinical use of antibiotics should be emphasized in the future to avoid the overuse of antibiotics.