|
|||||
|
|
HLA antigens and immunoglobulin allotypes in patients with malignant melanoma |
|
| Authors: | J.P. Pandey A.H. Johnson H.H. Fudenberg D.B. Amos J.U. Gutterman E.M. Hersh |
| Affiliation: | 1. Department of Basic and Clinical Immunology and Microbiology, Medical University of South Carolina, Charleston, South Carolina, USA;2. Division of Immunology, Duke University Medical Center, Durham, North Carolina, USA;3. Department of Developmental Therapeutics, M.D. Anderson Hospital and Tumor Institute, Texas Medical Center, Houston, Texas, USA |
| Abstract: | HLA antigens and Gm, A2m, and Km allotypes were examined in Caucasian patients with malignant melanoma. No significant associations were found for any of the HLA antigens tested. Significant association was found with Gm(2), and the relative risk for individuals with this marker was calculated at 1.9. The data indicate that Caucasians positive for Gm(2) are almost twice as likely to develop malignant melanoma as those without this marker. |
| Keywords: | Address requests for reprints to Dr. J.P. Pandey Department of Basic and Clinical Immunology and Microbiology Medical University of South Carolina 171 Ashley Avenue Charleston SC 29403. |
| 本文献已被 ScienceDirect 等数据库收录！ | |