| MMP-9在腺性膀胱炎及膀胱移行细胞癌组织中的表达与意义 |
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| 引用本文： | 张鑫圣,刘世雄,张颖,李玮,肖敦振.MMP-9在腺性膀胱炎及膀胱移行细胞癌组织中的表达与意义[J].浙江临床医学,2005,7(10):1011-1012. |
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| 作者姓名： | 张鑫圣 刘世雄 张颖 李玮 肖敦振 |
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| 作者单位： | [1]浙江省台州市中心医院泌尿外科,318000 [2]华中科技大学同济医学院,430000 |
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| 摘 要： | 目的研究基质金属蛋白酶-9（MMP-9）在腺性膀胱炎和膀胱移行细胞癌（TCCB）组织中的表达规律,探讨其与肿瘤的侵袭和转移关系.方法通过免疫组织化学的方法研究了15例腺性膀胱炎和27例膀胱移行细胞癌组织中MMP-9的表达情况,并以8例正常膀胱组织作对照. 结果 MMP-9在正常膀胱组织中不表达或微量表达,在腺性膀胱炎和膀胱移行细胞癌组织中呈不同程度的阳性表达. 结论 MMP-9在膀胱病变中发挥重要作用.
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| 关 键 词： | 基质金属蛋白酶 腺性膀胱炎 膀胱移行细胞癌 免疫组织化学 基质金属蛋白酶-9（MMP-9） 膀胱移行细胞癌 腺性膀胱炎 癌组织 免疫组织化学 膀胱组织 表达规律 表达情况 阳性表达 |
The expression and role of MMP-9 in cystitis glandularis and transitional cell carcinoma of bladder(TCCB) |
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| Zhang XingSheng.The expression and role of MMP-9 in cystitis glandularis and transitional cell carcinoma of bladder(TCCB)[J].Zhejiang Clinical Medical Journal,2005,7(10):1011-1012. |
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| Authors: | Zhang XingSheng |
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| Abstract: | Objective To study the expression of matrix metaUoproteinase - 9 in cystitis glandularis and transitional cell carcinoma of bladder, and investigate the relationship between tumor invasive capability and MMP - 9. Methods MMP - 9 was studied by immanohisteehemistry in 15 cystitis glandularis and 27 TCCB, and 8 normal bladder tissues as control. Results The expression of MMP - 9 was weak or negative in control group, positive in cystitis glandularis and TCCB. Conclusion MMP - 9 could play an important role in bladder diseases. |
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| Keywords: | matrix metalloproteinase cystitis glandularis transitional cell carcinoma of bladder immunohistochemistry |
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