| 肉苁蓉总苷对大鼠脑缺血再灌注后脑组织兴奋性氨基酸的作用 |
| |
| 引用本文： | 朱祖成.肉苁蓉总苷对大鼠脑缺血再灌注后脑组织兴奋性氨基酸的作用[J].安徽医药,2010,14(12):1393-1394. |
| |
| 作者姓名： | 朱祖成 |
| |
| 作者单位： | 湖北民族学院医学院,湖北,恩施,445000 |
| |
| 摘 要： | 目的观察肉苁蓉总苷（GCS）对SD大鼠脑缺血及再灌注损伤与脑组织兴奋性氨基酸（EAA）的影响。方法将SD大鼠经肉苁蓉总苷处理后,建立大鼠脑缺血再灌注模型,观察肉苁蓉总苷对脑组织中天冬氨酸（Glu）、谷氨酸（Asp）、γ-氨基丁酸（GABA）、甘氨酸（Gly）含量的影响。结果肉苁蓉总苷能够降低SD大鼠脑缺血再灌注后脑组织Glu的含量。结论肉苁蓉总苷抗缺血性脑损伤的作用机制可能与其对抗脑缺血及再灌注后EAA的升高有关。
|
| 关 键 词： | 肉苁蓉总苷 兴奋性氨基酸 脑缺血 再灌注 |
Effects of glycosides of cistanche on excitatory amino acid content in brain tissue of rats with cerebral ischemia and reperfusion |
| |
| ZHU Zu-cheng.Effects of glycosides of cistanche on excitatory amino acid content in brain tissue of rats with cerebral ischemia and reperfusion[J].Anhui Medical and Pharmaceutical Journal,2010,14(12):1393-1394. |
| |
| Authors: | ZHU Zu-cheng |
| |
| Institution: | ZHU Zu-cheng(Medical School of Hubei Institute for Nationalities,Enshi,Hubei 445000,China) |
| |
| Abstract: | Aim To observe the effects of glycosides of cistanche(GCs) on excitatory amino acid content in brain tissue of SD rats with cerebral ischemia and reperfusion.Methods The contents of glumatate(Glu),asparate(Asp),gama-aminobutyric acid(GABA) and glycine(Gly) in brain tissues were examined after cerebral ischemia and reperfusion SD rats.Results The GCs can reduce the content of Glu in brain tissue of SD rats with cerebral ischemia and reperfusion.Conclusion The mechanism of GCs in counteracting ischemic cerebr... |
| |
| Keywords: | glycosides of cistanche excitatory amino acid cerebral ischemia reperfusion |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
