Search for evidence of herpes simplex virus, type 1, or varicella-zoster virus infection in postmortem brain tissue from schizophrenic patients. |
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| Authors: | R C Alexander G Cabirac T Lowenkopf M Casanova J Kleinman R J Wyatt D G Kirch |
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| Affiliation: | Department of Psychiatry and Human Behavior, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107. |
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| Abstract: | The highly sensitive polymerase chain reaction (PCR) was used to search for herpes simplex virus type 1 (HSV-I) or varicella-zoster virus (VZV) in the DNA extracted from postmortem temporal cortex samples of 8 schizophrenic subjects, 8 nonschizophrenic suicide victims and 8 normal controls. HSV-I or VZV-specific DNA amplification was not detected in any of the samples studied. |
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| Keywords: | herpes simplex virus varicella-zoster virus schizophrenia polymerase chain reaction |
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