| 一种新的大鼠睡眠自动分析系统 |
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| 引用本文： | 靳照宇,库宝善,姚海燕,李中华,饶煜,王希勤.一种新的大鼠睡眠自动分析系统[J].中国药理学通报,1999,15(5):411-414. |
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| 作者姓名： | 靳照宇 库宝善 姚海燕 李中华 饶煜 王希勤 |
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| 作者单位： | 北京医科大学药理学系!北京100083(靳照宇，库宝善，姚海燕，李中华，饶煜王)，清华大学电子工程系信号处理学教研室!北京100084(希勤) |
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| 摘 要： | 目的 建立一种有效的大鼠睡眠自动分析系统。方法 采用数据采集软件记录大鼠脑电图、肌电图和眼电图，原始图形经去噪声压缩后用数据分析软件进行振幅分析和混合波导联分析，然后根据睡眠各时相特点，并利用一定的逻辑判断对睡眠成分进行分析。结果 人工分析和系统自动分析符合率达８５ ％ 以上；给予大鼠选择性增加深睡眠药物ｒｉｔａｎｓｅｒｉｎ，经自动系统分析所得结果与文献报道一致；随机选择相同大鼠对其ｄ １ 和ｄ ５ 相同时间段的睡眠时间进行比较，发现变化很小。结论 经检验，本系统具有的可信、稳定和准确等优点都达到国外同类软件先进水平
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| 关 键 词： | 睡眠自动分析系统 脑电图 肌电图 眼电图 振幅时间片直方图 门限 可信性 稳定性 准确性 |
A new automatic sleep analysis system in rats |
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| JIN Zhao Yu,KU Bao Shan,YAO Hai Yan,LI Zhong hua,RAO Yu,WANG Xi Qin.A new automatic sleep analysis system in rats[J].Chinese Pharmacological Bulletin,1999,15(5):411-414. |
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| Authors: | JIN Zhao Yu KU Bao Shan YAO Hai Yan LI Zhong hua RAO Yu WANG Xi Qin |
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| Institution: | JIN Zhao Yu,KU Bao Shan,YAO Hai Yan,LI Zhong hua,RAO Yu,WANG Xi Qin 1 |
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| Abstract: | AIM To set up an automatic sleep analyzing system for rats. METHODS In this system, the EEG, EMG, EOG are recorded and put into the computer. Then the system automatically conducts the amplitude (EEG, EMG and EOG) and hybridization analysis. According to the characteristics of each stages of sleep and using logical judgment, sleep is analyzed by the system. RESULTS Comparing the results of visual and automatic analysis of randomly selected time pieces, the rate of accordance is above 85%; using this system to analyze the effects of ritanserin on rats sleep, the results are in consistence with earlier report; comparing the sleep stages of the same rat on different days, the variance is negligible. CONCLUSION This system is proved to possess high credibility, stability and accuracy. |
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| Keywords: | automatic sleep analysis system EMG EOG EEG amplitude time pieces histograph threshold credibility stability accuracy |
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