Severe vitamin B-12 deficiency in a child mimicking thrombotic thrombocytopenic purpura |
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Authors: | Dimond Andrea George James N Hastings Caroline |
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Affiliation: | Department of Hematology Oncology, Children's Hospital Oakland, Oakland, California 94609, USA. adimond@gmail.com |
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Abstract: | We report a case of severe vitamin B-12 deficiency in a child who had a clinical presentation of hemolysis and thrombocytopenia that suggested the diagnosis of thrombotic thrombocytopenic purpura (TTP) and was associated with decreased ADAMTS13 activity. In this report, we review vitamin B-12 deficiency in children, the relationship between ADAMTS13 activity and TTP and discuss other conditions associated with decreased ADAMTS13 activity. |
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Keywords: | megaloblastic anemia vitamin B‐12 deficiency thrombotic thrombocytopenic purpura ADAMTS13 pediatric |
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