Colloid carcinoma of the pancreas: review of selected pathological and clinical aspects |
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Authors: | Liszka Lukasz Zielinska-Pajak Ewa Pajak Jacek Gołka Dariusz |
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Affiliation: | Department of Histopathology, Medical University of Silesia, Katowice, Poland. lliszka@mp.pl |
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Abstract: | Colloid carcinoma (CC) of the pancreas is a histopathological variant of ductal adenocarcinoma, which is characterised by the presence of large pools of extracellular mucin, containing neoplastic cells. The mucin component comprises at least 50% of CC (according to the definition by the World Health Organization) or at least 80% of the tumour (according to the US Armed Forces Institute of Pathology). In the vast majority of cases, CC develop from pre-existing intraductal papillary mucinous neoplasms, especially those forming intestinal-type papillae and characterised by MUC2 expression. Data concerning the long-term prognosis in patients with CC are discrepant. In this review, the authors present contemporary definitions of CC, issues of its epidemiology, symptomatology, pre-operative diagnostics, histopathology, treatment and prognosis. Special attention has been paid to pathogenesis of CC. |
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Keywords: | Colloid carcinoma mucinous carcinoma pancreatic cancer pancreatic neoplasms pancreas CC" },{" #name" :" keyword" ," $" :{" id" :" kw2115" }," $$" :[{" #name" :" text" ," _" :" colloid carcinoma DAC" },{" #name" :" keyword" ," $" :{" id" :" kw3115" }," $$" :[{" #name" :" text" ," _" :" ductal adenocarcinoma of the pancreas IOPN" },{" #name" :" keyword" ," $" :{" id" :" kw4115" }," $$" :[{" #name" :" text" ," _" :" intraductal oncocytic papillary neoplasms IPMN" },{" #name" :" keyword" ," $" :{" id" :" kw5115" }," $$" :[{" #name" :" text" ," _" :" intraductal papillary mucinous neoplasms MCN" },{" #name" :" keyword" ," $" :{" id" :" kw6115" }," $$" :[{" #name" :" text" ," _" :" mucinous cystic neoplasms PanIN" },{" #name" :" keyword" ," $" :{" id" :" kw5565" }," $$" :[{" #name" :" text" ," _" :" pancreatic intraepithelial neoplasia |
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