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CORRELATION OF vWF: Ag LEVELS WITH PULMONARY HYPERTENSION IN CONGENITAL HEART DEFECTS
引用本文:李筠,周爱卿.CORRELATION OF vWF: Ag LEVELS WITH PULMONARY HYPERTENSION IN CONGENITAL HEART DEFECTS[J].上海第二医科大学学报,1995(2).
作者姓名:李筠  周爱卿
作者单位:Shanghai Research Institute of Pediatrics,SSMU,Shanghai,200092
摘    要:CORRELATIONOFvWF:AgLEVELSWITHPULMONARYHYPERTENSIONINCONGENITALHEARTDEFECTSLiYun(李筠);zhouAiqing(周爱卿)(ShanghaiResearchInstitute...


CORRELATION OF vWF: Ag LEVELS WITH PULMONARY HYPERTENSION IN CONGENITAL HEART DEFECTS
Li Yun, zhou Aiqing.CORRELATION OF vWF: Ag LEVELS WITH PULMONARY HYPERTENSION IN CONGENITAL HEART DEFECTS[J].Journal of Shanghai Second Medical University(Foreign Language Edition),1995(2).
Authors:Li Yun  zhou Aiqing
Abstract:vWF: Ag is an important factor reflecting the injury of pulmonary vascular endothelium. We measured plasma concentrations of vWF: Ag in 89 patients with congenital heart defects (left to right shunting) by quantitative immunoelectrophoresis and assessed endothelial vWF: Ag directly by an immunoperoxidase stain applied io lung biopsy tissue in 10 patients. The patients with pulmonary hypertension had significanthigher vWF: Ag levels, the elevation was associated with the elevation of PVR (P<0.01). The vWF: Ag levels varied directly with PVR and PAR (r=0.89, 0.82, P<0.05).The regression equations of vWF: Ag-PVR. vWF: Ag-PAR we made cam help us to estimate PVR noninvasiverly. Our study will provide us a theoretical basis to choose an appropriate occasion for corrective suryery.
Keywords:von Willebrand factor  pulmonary hypertension  congenital heart defects
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