解脲支原体感染与男性不育

用双抗体夹心ＥＬＩＳＡ法检测解脲支原体，并与经典的培养法作了比较。３９例生育男性精浆解脲支原体ＥＬＩＳＡ法和培养法的阳性率分别为１０．３％和７．７％，１６４例不育者精浆解脲支原体两法阳性率分别为３５．４％和３１．７％，生育者与不育者解脲支原体阳性率差异非常显著（Ｐ＜０．００５）；ＥＬＩＳＡ法与培养法符合率为８６．５％。精子畸形率超过３０％及精子密度偏低（＜０．２亿／ｍｌ）的不育者，解脲支原体阳性率分别高达６９．２％和５６．５％。解脲支原体感染可导致精子形态与功能异常，从而引起男性不育。

Ureaplasma urealyticum infection and male infertility

Double-antibody sandwich ELISA was used for the detection of ureaplasma urealyticum,and was compared with classical culture method.The positive rates were 10.3%by ELISA and 7.7%by classical culture respectively in the seminal plasma of 39 fertile men,while they were 35.4%and 31.7%respectively in the seminal plasma of 164 infertile men.From these results,we found the difference of positive rates was significant in fertile and infertile men,and their identity rate was 86.5%. The positive rates of ureaplasma urealyticum were 69.2%and 56.5%respectively in the infertile men with their sperm morphological abnormality over 30%,and in those with their sperm density lower than 20 million/ml. Ureaplasma urealyticum infection may lead to male infertility due to the morphological and functional abnormalities of sperm caused by it.