Quality of life in patients of nasopharyngeal carcinoma: Validation of the Taiwan Chinese version of the EORTC QLQ-C30 and the EORTC QLQ-H&N35 |
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Authors: | Chie W.-C. Hong R.-L. Lai C.-C. Ting L.-L. Hsu M.-M. |
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Affiliation: | (1) School of Public Health and Graduate Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taiwan;(2) Department of Oncology, National Taiwan University Hospital, Taiwan;(3) Department of Radiotherapy, National Taiwan University Hospital, Taiwan;(4) Department of Otorhinol-aryngology, National Taiwan University Hospital, Taiwan |
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Abstract: | The authors followed the guidelines of translation and pilot testing of the EORTC QLQ-C30 and EORTC-QLQ-H&N35 questionnaires. The questionnaires were given to 50 nasopharyngeal carcinoma patients under active treatment and 50 under follow-up at our institution from November 2000 to June 2001. A retest was conducted 2 weeks after the first interview/form completion for the follow-up group. The intraclass correlation coefficients of the two questionnaires were moderate to high in the follow-up group. Cronbach's coefficients of all scales of the two questionnaires were 0.70 except that of cognitive functioning. Correlation of scales measuring similar dimensions of the QLQ-C30 and the SF-36 were moderate to high, while that of the QLQ-H&N35 and the QLQ-C30 and the SF-36 were moderate to low. Patients in the active treatment group had more serious acute problems due to disease and chemotherapy. Patients in the follow-up group had more serious chronic problems due to radiation therapy. We concluded that the Taiwan Chinese version of the EORTC QLQ-C30 and the EORTC QLQ-H&N35 had moderate to high test–retest reliability, high internal consistency in most scales, and could show the expected differences between patients in active treatment and follow-up group. |
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Keywords: | The EORTC QLQ-H& N35 The EORTC QLQ-C30 Nasopharyngeal carcinoma Quality of life |
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