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甲状腺球蛋白在促甲状腺激素刺激及抑制状态下对分化型甲状腺癌患者术后随访的价值
引用本文:马斌,任光辉,孙刚,马斌林. 甲状腺球蛋白在促甲状腺激素刺激及抑制状态下对分化型甲状腺癌患者术后随访的价值[J]. 新疆医科大学学报, 2011, 34(11): 1251-1253,1257
作者姓名:马斌  任光辉  孙刚  马斌林
作者单位:新疆医科大学附属肿瘤医院乳腺头颈外科,乌鲁木齐,830011
摘    要:目的了解分化型甲状腺癌(differentiated thyroid carcinoma,DTC)患者术后随访过程中,在不同促甲状腺激素(thyroid-stimulating hormone,TSH)状态下检测甲状腺球蛋白(thyroglobulin,TG)对于肿瘤复发或转移预测的意义。方法回顾性分析100例接受手术+131I治疗的DTC患者,其中TSH抑制组50例(A组),TSH刺激组50例(B组)。根据其是否转移或复发分为阳性组及阴性组,分别测定两组患者血清TG水平。结果 A组中阳性患者的血清TG水平为(15.35±19.42)μg/L,阴性患者的血清TG水平为(1.12±1.34)μg/L,差异有统计学意义(P=0.001)。B组中阳性患者的血清TG水平为(56.14±79.28)μg/L,阴性患者的血清TG水平为(20.02±33.76)μg/L,差异有统计学意义(P=0.001)。两组间复查阳性患者及复查阴性患者间血清TG水平的差异均无统计学意义(P>0.05)。结论血清TG水平在TSH抑制或刺激情况下对于监测甲状腺癌的复发和转移均具有一定的指导意义。

关 键 词:甲状腺癌  甲状腺球蛋白  促甲状腺激素

The value of monitoring thyroglobulin during the follow-up period in thyroid-stimulating hormone stimulation and inhibit state of differentiated thyroid cancer patients
MA Bin,REN Guang-hui,SUN Gang,MA Bin-lin. The value of monitoring thyroglobulin during the follow-up period in thyroid-stimulating hormone stimulation and inhibit state of differentiated thyroid cancer patients[J]. Journal of Xinjiang Medical University, 2011, 34(11): 1251-1253,1257
Authors:MA Bin  REN Guang-hui  SUN Gang  MA Bin-lin
Affiliation:MA Bin,REN Guang-hui,SUN Gang,MA Bin-lin(Deparment of Breast & Neck Surgery,A f filiated Tumor Hospital,Xinjiang Medical University,Urumqi 830011,China)
Abstract:Objective To discuss the prediction significance for tumor recurrence or metastasis for testing thyroid globulin(state thyroglobulin,TG) in different state of thyroid-stimulating hormone(TSH) during the follow-up period of differentiated thyroid carcinoma(DTC) patients.Methods A retrospective analysis was done in 100 cases of DTC patients who received surgical resection and 131I radioiodine therapy.All cases were divided into TSH inhibit group of 50 cases(group A) and TSH stimulate group of 50 cases(group B...
Keywords:thyroid carcinoma  thyroglobulin  thyroid-stimulating hormone  
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