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Cholelithiasis in Down's syndrome
Authors:Toscano E  Trivellini V  Andria G
Affiliation:Department of Paediatrics, "Federico II" University, Via S. Pansini 5, I-80131 Naples, Italy.
Abstract:Cholelithiasis is considered uncommon in infancy, childhood, and adolescence. We performed a prospective, controlled study showing that children with Down's syndrome have a significantly higher prevalence of cholelithiasis (4.7%) compared with controls (0.2%). Clinicians should be aware of the risk of gallstones in children with Down's syndrome.
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