| 双黄连粉针剂体外抗病毒药效学研究 |
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| 引用本文： | 易世红,王放,王丽萍,赵春燕,魏强,李凡.双黄连粉针剂体外抗病毒药效学研究[J].吉林大学学报(医学版),2001,27(5):490-492. |
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| 作者姓名： | 易世红 王放 王丽萍 赵春燕 魏强 李凡 |
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| 作者单位： | 1. 吉林大学基础医学院病原生物学教研室
2. 吉林大学第一医院病理科 |
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| 摘 要： | 目的 :明确双黄连粉针剂抗病毒作用谱及体外抗病毒作用机理。方法 :采用组织细胞培养法、染料摄入法检测双黄连粉针剂对各种病毒的作用 ,改变给药时间、途径 ,探讨双黄连粉针剂抗病毒作用环节。结果 :双黄连粉针剂具有明显抗流感病毒、呼吸道合胞病毒、腺病毒 型、单纯疱疹病毒 、 型、柯萨奇病毒 B3 、柯萨奇病毒 B4 、柯萨奇病毒 A16、新型肠道病毒 71型的作用 ;对脊髓灰质炎病毒 型、埃可病毒 6型、麻疹病毒、水泡性口炎病毒有一定的抑制作用 ;双黄连粉针剂与鱼腥草针剂相比 ,其抗病毒效果显著。结论 :双黄连粉针剂是一种较广谱的抗病毒针剂 ,抗病毒作用广泛。
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| 关 键 词： | 双黄连 抗病毒 细胞病变 |
| 文章编号： | 0253-3707(2001)05-0490-03 |
| 修稿时间： | 2000年10月25日 |
Curative effect of Shuanghuanglian injection on anti-virus in vitro |
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| YI Shi hong ,WANG Fang ,WANG Li ping ,ZHAO Chun yan ,WEI Qiang ,LI Fan.Curative effect of Shuanghuanglian injection on anti-virus in vitro[J].Journal of Jilin University: Med Ed,2001,27(5):490-492. |
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| Authors: | YI Shi hong WANG Fang WANG Li ping ZHAO Chun yan WEI Qiang LI Fan |
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| Institution: | YI Shi hong 1,WANG Fang 1,WANG Li ping 2,ZHAO Chun yan *,WEI Qiang 1,LI Fan 1 |
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| Abstract: | Objective:To explicate effect spectrum and anti virus mechanism of Shanghuanglian in vitro .Methods:The inhibition effect of Shanghaunglian on various virus was observed with the method of tissue and cell culture,absorption of dye,and the anti virus effect of Shuanghuanglian Fenzhenji was studied by using medicine at different time.Results:Shanghuanglian had obvious anti virus effect on influenza virus,respiratory syncytical virus,Adenovirus Ⅲ,Herpes simplex virus Ⅰ,Ⅱ,Coxsackie virus,B 3,B 4,A 16 and had more distinct and stable effect than Houttuyniae Cordatae.It also had a little anti virus effect on poliovirus Ⅲ,ECHO virus 6,measles virus.Conclusion:Shuanghuanglian is a wide spectrum anti virus injection and has multimedia anti virus effect. |
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| Keywords: | Shuanghuanglian anti virus cytopathic effect |
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