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Effects of lysine on toxicity and depressant effects of ethanol in rats
Authors:C O Ward  C A Lau Cam  A S Tang  R J Breglia  C I Jarowski
Affiliation:1. Department of Pharmacology, St. John''s University, College of Pharmacy, Jamaica, New York 11432 USA;2. Department of Pharmaceutics, St. John''s University, College of Pharmacy, Jamaica, New York 11432 USA
Abstract:When l-lysine was administered prior to toxic doses of ethanol, the LD50 for ethanol was slightly increased after both po and ip administration. The onset of ethanol-induced sleeping time was prolonged while the duration was reduced by pretreatment with l-lysine.
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