Effects of lysine on toxicity and depressant effects of ethanol in rats |
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Authors: | C O Ward C A Lau Cam A S Tang R J Breglia C I Jarowski |
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Affiliation: | 1. Department of Pharmacology, St. John''s University, College of Pharmacy, Jamaica, New York 11432 USA;2. Department of Pharmaceutics, St. John''s University, College of Pharmacy, Jamaica, New York 11432 USA |
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Abstract: | When l-lysine was administered prior to toxic doses of ethanol, the LD50 for ethanol was slightly increased after both po and ip administration. The onset of ethanol-induced sleeping time was prolonged while the duration was reduced by pretreatment with l-lysine. |
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