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The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl) thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism
Authors:Francesca Tonelli  Manal Alossaimi  Leon Williamson  Rothwelle J Tate  David G Watson  Edmond Chan  Robert Bittman  Nigel J Pyne  Susan Pyne
Institution:1.Cell Biology and Pharmaceutical Analysis and Metabolomics Groups, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK;2.Department of Chemistry and Biochemistry, Queens College of the City University of New York, New York, USA
Abstract:
Keywords:sphingosine 1-phosphate  sphingosine kinase  androgen receptor  reactive oxygen species  prostate cancer
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