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Sudden-onset unilateral painless vision loss
Institution:1. Vitreoretinal Surgery (VRS), P.L.L.C., Edina, MN, USA;2. Department of Ophthalmology and Visual Neurosciences, University of Minnesota Medical School, Minneapolis, MN, USA;3. Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, San Diego, CA, USA;1. MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal;2. CINTESIS—Center for Health Technology and Services Research, Porto, Portugal;3. RISE—Health Research Network, Porto, Portugal;4. Department of Ophthalmology, Centro Hospitalar Universitário do Porto, Porto, Portugal;5. Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Porto, Portugal;6. Department of Ophthalmology, School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal;7. Department of Ophthalmology, University Hospital Center of S. João, Porto, Portugal;8. Unit of Pharmacology and Therapeutics, Department of Biomedicine, Faculty of Medicine, University of Porto, Porto, Portugal;9. MedInUP—Center for Drug Discovery and Innovative Medicines, University of Porto, Porto, Portugal;1. Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia;2. Department of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands;3. Moorfields Eye Hospital, NHS Foundation Trust, London, UK;4. University College London Institute of Ophthalmology, London, UK;5. Singapore National Eye Centre, Singapore;6. Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;7. Postgraduate Institute of Medical Education and Research, Chandigarh, India;8. Department of Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore;9. Singapore Eye Research Institute, Singapore;10. National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore;11. Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore;1. Division of Ophthalmology, St John Eye Hospital/Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, South Africa;2. Department of Pediatrics, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, South Africa;3. Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit (VIDA), Faculty of Health Sciences, University of the Witwatersrand, South Africa;1. Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada;2. Faculty of Medicine, Department of Ophthalmology and Visual Sciences, University of Toronto, Toronto, Ontario, Canada;3. Faculty of Medicine, Department of Medicine, Division of Neurology, University of Toronto, Toronto, Ontario, Canada
Abstract:A 75-year-old Caucasian woman presented with sudden-onset multifocal scotomas in her right eye's central vision for 1 day. There were subtle white intraretinal foveal lesions that correlated with patchy inner retinal hyperreflectivity on optical coherence tomography, suggestive of paracentral acute middle maculopathy. Initial cerebrovascular work-up was negative. Review of systems was positive for lethargy and jaw claudication. The sedimentation rate and c-reactive protein were elevated, but platelet count was normal. The patient was started on 60 mg oral prednisone daily and underwent bilateral temporal artery that confirmed the diagnosis of giant cell arteritis.
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