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Association of Kidney Function Measures With Signs of Neurodegeneration and Small Vessel Disease on Brain Magnetic Resonance Imaging: The Atherosclerosis Risk in Communities (ARIC) Study
Institution:1. Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland;2. Division of Nephrology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland;3. Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland;4. Department of Nephrology, Charité Universitätsmedizin Berlin, Berlin, Germany;5. The MIND Center, University of Mississippi Medical Center, Jackson, Mississippi;6. Department of Neurology, Mayo Clinic, Rochester, Minnesota;7. Stanley Steyer School of Health Professions, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;8. Current affiliation: National Institute of Neurological Disorders and Stroke Intramural Research Program, Bethesda, Maryland;1. University of Cyprus Medical School, University of Cyprus, Nicosia, Cyprus;2. Center of Excellence in Biobanking and Biomedical Research, biobank.cy, Nicosia, Cyprus;1. Division of Nephrology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland;2. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland;3. Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center at Houston, Houston, Texas;1. Department of Medicine, University of Illinois at Chicago, Chicago, Illinois;2. Department of Medicine, University of Chicago, Chicago, Illinois;3. Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana;1. Department of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India;2. Department of Radio-diagnosis and Imaging, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India;1. Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, Australia;2. Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan;3. III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;4. Monash Micro Imaging, Monash University, Clayton, Australia;5. Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan;6. Australian Research Council (ARC) Training Centre for Cell and Tissue Engineering Technologies, Melbourne, Australia;1. Department of Medicine, Tufts Medical Center, Boston, Massachusetts;2. Section of Geriatric Medicine, Division of Primary Care and Population Health, Stanford University, Stanford, California;3. Geriatric Research and Education Clinical Center, Palo Alto Veterans Affairs Health Care System, Palo Alto, California;4. Department of Medicine, School of Medicine, Tufts University, Boston, Massachusetts;5. Jean Mayer Human Nutrition Research Center on Aging, US Department of Agriculture, Boston, Massachusetts;6. Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland;7. Geriatric Research and Education Clinical Center, VA Maryland Healthcare System, Baltimore, Maryland;8. Department of Surgery and Perioperative Care, Dell Medical School, University of Texas at Austin, Austin, Texas
Abstract:
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  • Keywords:Albuminuria  Atherosclerosis Risk in Communities (ARIC) Study  brain infarcts  cerebral small vessel disease  chronic kidney disease (CKD)  creatinine  cystatin C  diffusion tensor imaging  estimated glomerular filtration rate (eGFR)  magnetic resonance imaging (MRI)  microhemorrhages  neurodegeneration  urinary albumin-creatinine ratio (UACR)  white matter lesions
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