Real-Time PCR Quantification of Methanobrevibacter oralis in Periodontitis |
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| Authors: | Amélie Bringuier Saber Khelaifia Hervé Richet Gérard Aboudharam Michel Drancourt |
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| Affiliation: | aAix Marseille Université, URMITE, UMR63 CNRS 7278, IRD 198, Inserm 1095, Marseille, France;bUFR Odontologie, Aix-Marseille Université, Marseille, France |
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| Abstract: | A real-time PCR assay developed to quantify Methanobrevibacter oralis indicated that its inoculum significantly correlated with periodontitis severity (P = 0.003), despite a nonsignificant difference in prevalence between controls (3/10) and patients (12/22) (P = 0.2, Fisher test). The M. oralis load can be used as a biomarker for periodontitis. |
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