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Risk of hepatic decompensation but not hepatocellular carcinoma decreases over time in patients with hepatitis B surface antigen loss
Affiliation:1. Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong;2. Medical Data Analytics Centre (MDAC), The Chinese University of Hong Kong, Hong Kong;3. Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong;4. Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong;5. Department of Internal Medicine, Union Hospital, Hong Kong;1. APHP, Liver Unit, Bobigny, Université Sorbonne Paris Nord, F-93000 Bobigny, France;2. APHP, Biochemistry Unit, Bobigny, Université Sorbonne Paris Nord, and Inserm, UMR-1148 “Laboratory for Vascular Translational Science” Université Sorbonne Paris Nord, F-93000 Bobigny, France;3. Univ Paris Est Créteil, INSERM, IMRB, Equipe CEpiA (Clinical Epidemiology and Ageing), Unité de Recherche Clinique (URC Mondor), Service de Santé Publique, Assistance Publique Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Henri Mondor, F-94000, Créteil, France;4. Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, CUB Hopital Erasme, and Laboratory of Experimental Gastroenterology, Université Libre de Bruxelles, Brussels, Belgium;5. Inserm, UMR-1138 “Functional Genomics of Solid Tumors”, Centre de Recherche des Cordeliers, Université de Paris, Paris, France;6. Clinical Research Department, ANRS|Emerging Infectious Diseases, Paris, France;7. SBIM, APHP, Hôpital Saint-Louis, Paris, Inserm, UMR-1153, ECSTRA Team, Paris, France;8. APHP, Pathology Unit, Bobigny, Université Sorbonne Paris Nord, F-93000 Bobigny, France;1. Cardinal Santos Medical Cente, Manila, Philippines;2. Division of Gastroenterology and Hepatology, National University Hospital, National University Health System, Singapore;3. Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;4. Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Biopolis, Singapore;1. Infectious Disease Discovery;2. Lead Discovery;3. Medicinal Chemistry;4. Pharmaceutical Sciences;5. Preclinical Chemistry Manufacturing and Controls;6. Data & Analytics, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Shanghai, Roche Innovation Center Basel;1. Division of Infectious Diseases, Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centers, Location University of Amsterdam, the Netherlands;2. Department of Medical Microbiology and Infection Prevention, Amsterdam University Medical Centers, Location University of Amsterdam, the Netherlands;1. Stravitz-Sanyal Institute for Liver Disease and Metabolic Health, Virginia Commonwealth University School of Medicine, Richmond, VA, USA;2. Clinical R&D, SomaLogic Inc., Boulder, CO, USA;3. Dept. of Pediatrics, Columbia University, New York, NY, USA;4. Division of Gastroenterology, Saint Louis University School of Medicine, St. Louis, MO, USA;5. Applied Modeling, SomaLogic, Inc., Boulder, CO, USA;6. Liver Institute Northwest, Seattle, WA, USA;7. Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA;8. Division of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH, USA;9. Division of Gastroenterology and Hepatology, Duke University School of Medicine, Durham, NC, USA;10. NAFLD Research Center, University of California San Diego School of Medicine, San Diego, CA, USA;11. Division of Gastroenterology and Hepatology, University of California San Francisco School of Medicine, San Francisco, CA, USA;12. Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA;13. Dept. of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA;14. Business Development, SomaLogic Inc, Boulder, CO, USA;15. Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA;1. Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK;2. Division of Gastroenterology and Hepatology, Department of Internal Medicine, The National University Hospital of Iceland, Reykjavik, Iceland;3. UGC Digestivo y Servicio de Farmacología Clínica, Instituto de Investigación Biomédica de Málaga (IBIMA_Plataforma Bionand), Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, Spain;4. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain;5. NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, UK
Abstract:
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  • Keywords:HBsAg seroclearance  hepatic decompensation  hepatitis B virus  liver cancer
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