| MRI监控HIFU损伤活体兔肝VX2瘤的影像学观察 |
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| 引用本文： | 沈洁.MRI监控HIFU损伤活体兔肝VX2瘤的影像学观察[J].重庆医学,2012,41(9):840-841,844. |
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| 作者姓名： | 沈洁 |
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| 作者单位： | 沈洁 (重庆市妇幼保健院B超室,400013) ； |
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| 摘 要： | 目的观察高强度聚焦超声(HIFU)损伤20例活体兔肝VX2瘤的磁共振成像(MRI)监控图像,探讨MRI图像变化及其与实际损伤的关系。方法 HIFU以点辐照的方式逐层覆盖20例活体兔肝VX2瘤,并在HFIU术前及术后即刻扫描快速自旋回波(TSE)序列T1加权像(T1WI)、T2WI及增强T1WI。观察MRI图像变化,并取瘤体组织作2,3,5-氯化三苯基四氮唑(TTC)染色及苏木素-伊红染色,进行病理检查。结果 MRI图像改变能较准确地反映HIFU术后即刻瘤体内部损伤情况。结论 MRI能有效监控及评价HIFU损伤活体兔肝VX2瘤的效果。
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| 关 键 词： | 磁共振成像 肝肿瘤 实验性 高强度聚焦超声 兔 |
Imaging observation of MRI guided HIFU destroying rabbit liver VX2 tumor in vivo |
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| Shen Jie.Imaging observation of MRI guided HIFU destroying rabbit liver VX2 tumor in vivo[J].Chongqing Medical Journal,2012,41(9):840-841,844. |
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| Authors: | Shen Jie |
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| Institution: | Shen Jie(Department of B Ultrasound,Chongqing Health Center For Women and Children,Chongqing 400013,China) |
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| Abstract: | Objective To observe the magnetic resonance imaging(MRI) monitoring images of liver VX2 tumors which were destroyed by high intensity focused ultrasound(HIFU) in 20 rabbits in vivo and to explore the changes of MRI images and their relation to the actual damage.Methods HIFU irradiation covered liver VX2 tumors of 20 rabbits,layer by layer in way of focus point.T1-weighted image(T1WI),T2WI and enhanced T1WI of turbo spin-echo(TSE) sequence were performed before and instantly after HIFU treatment.Changes of MRI image were observed.Tumor tissue were taken for pathological examination using 2,3,5-triphenyl-2H-tetrazolium chloride(TTC) staining and hematoxylin-eosin staining.Results MRI images could accurately reflect the internal lesions in tumor immediately after HIFU treatment.Conclusion MRI can effectively monitor and evaluate the effects of HIFU on destroying rabbit liver VX2 tumor in vivo. |
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| Keywords: | magnetic resonance imaging liver neoplasms experimental high intensity focused ultrasound rabbits |
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