| Bcl-2/Fas与子宫内膜异位症发病关系的研究 |
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| 引用本文： | 毛熙光,林海蕤,高谨,秦明丽,邱盛洪. Bcl-2/Fas与子宫内膜异位症发病关系的研究[J]. 中国现代医学杂志, 2004, 14(22): 57-58,70 |
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| 作者姓名： | 毛熙光 林海蕤 高谨 秦明丽 邱盛洪 |
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| 作者单位： | 四川泸州医学院附属医院,妇产科,四川,泸州,646000 |
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| 摘 要： | 目的研究Bcl-2/Fas基因蛋白与子宫内膜异位症的发病关系.方法用免疫组化ABC法检测了40例正常子宫内膜和46例子宫内膜异位症患者.结果子宫内膜异位症患者的内膜组织中的表达评分(172.4±87.6)明显高于正常子宫内膜中的表达评分(106.2±118.1),有显著性差异(P＜0.05);Fas基因蛋白在子宫内膜异住患者异位内膜细胞中的表达评分(207.6±100.2)与正常子宫内膜上皮中的表达评分(119.3±91.3)无显著性差异(P＞0.05).结论Bcl-2基因与子宫内膜异位症的发生有一定关系,Fas基因对子宫内膜异位症的发生关系有待于进一步研究.
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| 关 键 词： | 子宫内膜异位症 细胞凋亡 基因表达 |
| 文章编号： | 1005-8982(2004)22-0057-02 |
Relation between Bcl-2/Fas gene and pathogenesis of endometriosis |
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| MAO Xi-guang,LIN Hai-rui,GAO Jing,QING Ming-li,QIU Sheng-hong. Relation between Bcl-2/Fas gene and pathogenesis of endometriosis[J]. China Journal of Modern Medicine, 2004, 14(22): 57-58,70 |
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| Authors: | MAO Xi-guang LIN Hai-rui GAO Jing QING Ming-li QIU Sheng-hong |
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| Abstract: | Objective:To research whether the endometriosis is associated with Bcl-2and Fas gene.Methods:Immunohistochemisty me test(ABC methods)was used to detect the expression of Bcl-2and Fs gene in40speci-mens of normal endometrium tissue and46specimens of endometriosis tissue.Results:In the endometriosis group,the positive rate of Bcl-2gene was significantly higher than that of the normal endometrium group(P<0.05);the rate of Fas gene was no significantly difference with that of the normal group(P>0.05).Conclusions:The study sug-gestes that Bcl-2gene is relate with endometriosis;more study should be done to find the relation between Fas gene and endometriosis. |
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| Keywords: | Bcl-2:Fas |
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