实验室指标对急性胰腺炎患者并发症与生存状况的预测效果研究

目的:探讨实验室指标对急性胰腺炎患者并发症与生存状况的预测效果。方法:选取我院2015年2月~2018年2月收治的AP患者236例为研究对象。统计患者实验室检测指标,包括红细胞分布宽度(RDW)、白细胞计数(WBC)、超敏C反应蛋白(hs-CRP)、降钙素原(PCT)和白蛋白(Alb)。记录患者并发症发生情况和死亡情况。结果:根据是否发生并发症,分为并发症组和非并发症组,并发症组PCT、RDW、hs-CRP、WBC显著高于非并发症组(P<0.05),而Alb显著低于非并发症组(P<0.05)。多因素Logistic回归分析显示,PCT、hs-CRP、WBC是AP患者发生并发症的独立危险因素3236例AP患者治疗1个月内死亡22例,占9.32%。根据生存状况,分为存活组和死亡组,死亡组PCT、RDW、hs-CRP、WBC显著高于存活组(P<0.05),而Alb显著低于存活组(P<0.05)。多因素Logistic回归分析显示,PCT和hs-CRP是AP患者死亡的独立危险因素。结论:PCT、hs-CRP、WBC是AP患者发生并发症的独立危险因素,PCT和hs-CRP是AP患者死亡的独立危险因素。

Predictive effect of laboratory indicators on complications and survival of patients with acute pancreatitis

Objective:To investigate the predicrive effect of laboratory indicators on complications and survival of patients with acute pancreatitis.Methods:A total of 236 patients with AP were enrolled in our hospital from February 2015 to February 2018.Statistical indicators of laboratory tests for patients included red blood cell distribution width(RDW),white blood cell count(WBC),high-sensitivity C-reactive protein(hs-CRP),procalcitonin(PCT),and albumin(Alb).The patient complications and deaths data was recorded.Results;According to complications occurred or not,it was divided into complicarion group and non-complication group.The PCT,RDW,hs-CRP and WBC in complication group were significantly higher than those in non-complication group(P<0.05),while Alb was significantly lower than non-concurrence group(P<0.05).Multivariate Logistic regression analysis showed that PCT,hs-CRP and WBC were independent risk factors for complications in patients with AP.In 236 patients with AP,22 patients died within 1 month after treatment,accounting for 9.32%.According to the survival condition,the patients were divided into survival group and death group.The PCT,RDW,hs-CRP and WBC in the death group were significantly higher in the death group than the survival group(P<0.05),while Alb was significantly lower than the survival group(P<0.05).Multivariate logistic regression analysis showed that PCT and hs-CRP were independent risk factors for death in patients with AP.Conclusion:PCT,hs-CRP and WBC are independent risk factors for complications in patients with AP.PCT and hs-CRP are independent risk factors for death in patients with AP.