重复经颅磁刺激对脑卒中后认知功能障碍患者认知功能、中枢运动传导时间及平衡能力的影响

目的:探究重复经颅磁刺激(rTMS)对脑卒中后认知功能障碍患者认知功能、中枢运动传导时间及平衡能力的影响。方法:选取脑卒中后认知功能障碍患者200例，随机分为4组，每组50例患者，对照组给予常规基础治疗及认知功能训练，低频组在对照组基础上增加低频rTMS,高频组在对照组基础上增加高频rTMS,联合组在对照组基础上增加高低频双侧rTMS。对4组患者治疗前后的认知功能、中枢运动传导时间及平衡能力进行对比分析。结果:治疗后，4组患者的简易智能状态检查量表(MMSE)、蒙特利尔认知评估量表(MoCA)、Berg平衡功能量表(BBS)、Barthel指数(MBI)评分均较治疗前明显上升(P<0.05),中枢运动传导时间下降(P<0.05),且联合组MMSE、MoCA、BBS、MBI评分显著高于其他组，中枢传导时间显著低于其他组(P<0.05),对照组MMSE、MoCA、BBS、MBI评分显著低于其他组，中枢传导时间显著高于其他组(P<0.05)。结论:低频联合高频rTMS对脑卒中后认知功能障碍患者有较好治疗效果，可以显著改善患者的认知功能及平衡能力，缩短中枢运动传导时间，...

Effects of repetitive transcranial magnetic stimulation on cognitive function, central motor conduction time and balance ability in patients with post-stroke cognitive impairment

Objective: To explore the effects of repetitive transcranial magnetic stimulation (rTMS) on cognitive function, central motor conduction time and balance ability in patients with post-stroke cognitive impairment. Methods: Totally, 200 patients with post-stroke cognitive impairment were randomly divided into 4 groups, 50 patients in each group. The control group was given conventional basic treatment and cognitive function training, the low-frequency group was given low-rTMS on the basis of the control group, the high-frequency group was given high-rTMS on the basis of the control group, and the combined group was given high and low rTMS on the basis of the control group. The cognitive function, central motor conduction time and balance ability of the 4 groups after treatment were compared and analyzed. Results: Before treatment, there was no significant difference among the 4 groups in the comparison of the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment Scale (MoCA), Berg Balance Scale (BBS), Modified Barthel Index (MBI), and central motor conduction time (P>0.05). After treatment, the MMSE, MoCA, BBS, and MBI scores in the 4 groups all increased, and the central motor conduction time decreased. After treatment, the MMSE, MoCA, BBS and MBI scores in the combined group were significantly higher, and the central motor conduction time was significantly shorter than in the other groups (P<0.05); The MMSE, MoCA, BBS, and MBI scores in the control group were significantly lower, and the central motor conduction time was significantly shorter than those in the other groups (P<0.05). Conclusion: Low frequency combined with high frequency rTMS has a good therapeutic effect on patients with post-stroke cognitive impairment, which can significantly improve the cognitive function and balance ability of patients, shorten the central motor conduction time, and improve the ability of daily living activities.