Vascular endothelial function and plasma homocysteine levels in Behcet's disease |
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| Authors: | Ozdemir Ramazan Barutcu Irfan Sezgin Alpay T Acikgoz Nusret Ermis Necip Esen Ali Metin Topal Ergun Bariskaner Emrah Ozerol Ibrahim |
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| Affiliation: | Department of Cardiology, Faculty of Medicine, Inonu University, Turgut Ozal Medical Center, Malatya, Turkey. rozdemir@inonu.edu.tr |
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| Abstract: | The purpose of the present study was to test endothelial function and to determine if plasma homocysteine levels are associated with endothelial injury in patients with Behcet's disease (BD). Flow-mediated dilation in patients with BD was smaller than that of control subjects (p = 0.001), and mean plasma homocysteine levels in patients with BD were significantly higher (p = 0.0001). On regression analysis, only mean plasma homocysteine concentration was independently related to flow-mediated dilation (F = 5.7, p = 0.001). |
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