广州市中小学生血红蛋白与血压水平的相关性

目的探讨中小学生血红蛋白与血压水平的相关性,为制定高血压防治措施提供依据。方法采用整群抽样的方法,选取2015年广州市11区101所中小学校的34752名学生为研究对象,通过线性回归分析及Logistic回归分析探讨血红蛋白与血压的相关性。结果男、女生贫血检出率分别为3.2%和9.6%,差异有统计学意义(χ^2=611.85,P<0.01)。相关分析显示,仅贫血组女生的血红蛋白与收缩压呈负相关(r=-0.06,P<0.01),其余贫血组学生的血红蛋白与血压均不存在相关关系(P值均>0.05);非贫血组学生的血红蛋白与收缩压和舒张压均呈正相关(P值均<0.01)。线性回归分析显示,在总人群、男生、女生中,血红蛋白水平对收缩压和舒张压均起正向作用(P值均<0.01)。Logistic回归分析显示,与血红蛋白水平Q2组的同年级学生比较,血红蛋白水平Q4组的小学生、Q3和Q4组的初中和高中学生高血压前期和高血压的患病风险显著增加(P值均<0.05)。结论在非贫血人群中,血红蛋白与收缩压和舒张压之间存在正相关关系。

Correlation between hemoglobin and blood pressure in primary and middle school students in Guangzhou

Objective To explore the correlation between hemoglobin and blood pressure.Methods This study adopted the cross-sectional design method.Participants were recruited from grade 2 in primary school,grade 1 from junior and senior high school taking physical examination,including the hemoglobin test,organized by the Guangzhou Municipal Primary and Secondary School Health and Health Promotion Center from January to December in 2015.Correlation between blood pressure and hemoglobin and determinants of blood pressure were analyzed.Results A total of 34 752 samples participated including 17 414 boys and 17 338 girls.Hemoglobin was negatively associated with systolic blood pressure(SBP)and diastolic blood pressure(DBP)among girls with anemia(P<0.01).Hemoglobin was positively associated with SBP and DBP among boys and girls with normal hemoglobin level(P<0.01).With each tertile increase in blood pressure,hemoglobin level increased by 1 mmHg.Logistic regression analysis showed that compared with peers from same grade with hemoglobin level lower than P25,the risk of suffering from pre-hypertension and hypertension among students from grade 2 with hemoglobin level greater than or equal to P75,and those from junior high and senior high schools with hemoglobin level higher than or equal to P50.Conclusion Among students without anemia population,a positive correlation between hemoglobin and SBP and DBP is observed.