The Science behind Topical Negative Pressure Therapy |
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Authors: | C Weston |
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Institution: | Clinical Marketing Manager, Northern Europe, KCI Medical Ltd., KCI House, Langford Locks, Kidlington, Oxford, OX5 1GF. |
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Abstract: | Topical negative pressure therapy (TNP) is an established part of modern wound healing. With an increasing choice in TNP providers, understanding the differing modes of action, the biochemical and biophysical effects on the wound at a microscopic and macroscopic level, plus the role of the interface dressings, will aid the clinician in planning a clear goal of therapy. This article reviews the scientific evidence for TNP to date and explores each mechanism of action and the implications for wound healing and patient outcomes. |
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Keywords: | Topical negative pressure therapy V A C ® Therapy matrix metalloproteinase cytokines microvascular blood flow perfusion cell strain |
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