不同剂量的异丙酚在无痛人工流产时对呼吸功能的影响

目的：观察不同剂量的异丙酚在无痛人工流产时对呼吸功能的影响。方法：随机选择行无痛人工流产的患者60例,年龄20～44岁,ASAⅠ～Ⅱ级,静脉推注异丙酚镇痛。按异丙酚剂量分为两组,Ⅰ组用量1.5mg/kg（30例）;Ⅱ组用量2.0mg/kg（30例）。观察用药后呼吸暂停时间和恢复时间,测定给药1～10min呼吸的变化并记录。结果：大剂量的异丙酚可致呼吸暂停,且呼吸恢复时间明显减慢。结论：异丙酚对呼吸影响较大,有抑制呼吸作用,并可致呼吸暂停,应由专业医师使用。

Influence of different doses of Diprivan on respiratory function at induced abortion

Objective： To observe the effect of different doses of Diprivan on respiratory function at induced abortion. Methods： 60 patients of ASAⅠ-Ⅱ between the ages of 20 and 44, who required induced abortion at random, and intravenously push Diprivan into their body to ease pain. They were divided into two groups according to different doses of Diprivan, Group Ⅰ, 1.5 mg/kg （30 cases）; Group Ⅱ, 2.0 mg/kg （30 cases）. The time of apnoea and recovery after medication were observed and the changes of breathing 1 to 10 minutes later were measured and recorded. Results： A high dose of Diprivan could lead to apnoea and the recovery time of spontaneous breathing was obviously longer. Conclusion： Diprivan can affect breathing and it can lead to apnoea and should be used by specialist physicians.