| 激光立体成形镍铬烤瓷合金的生物安全性评价 |
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| 引用本文： | 贾艳,高勃.激光立体成形镍铬烤瓷合金的生物安全性评价[J].第三军医大学学报,2009,31(8). |
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| 作者姓名： | 贾艳 高勃 |
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| 作者单位： | 第四军医大学口腔医学院修复科,西安,710032 |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 目的 评价激光立体成形Ni-62.9Cr-23烤瓷合金的生物安全性.方法 参照GB/T16886-2003和YY/T0279-1995以及YY/T0244-1996标准对激光立体成形镍铬烤瓷合金进行4种体内外实验,即细胞毒性实验、短期全身毒性实验、溶血实验及口腔黏膜刺激实验.结果 激光立体成形Ni-62.9Cr-23烤瓷合金细胞毒性实验评级为0～1级,无明显细胞毒性作用,未见任何短期伞身毒性反应,溶血程度为0.385%,口腔黏膜刺激实验未见异常组织学反应.结论 由以上结果可以初步认为激光立体成形Ni-62.9Cr-23烤瓷合金具有良好的生物安全性,是一种理想的生物材料.
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| 关 键 词： | 激光立体成形 镍铬合金 生物安全性 牙科材料 |
Biological safety of Ni-Cr alloy fabricated by laser solid forming technology |
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| JIA Yan,GAO Bo.Biological safety of Ni-Cr alloy fabricated by laser solid forming technology[J].Acta Academiae Medicinae Militaris Tertiae,2009,31(8). |
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| Authors: | JIA Yan GAO Bo |
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| Institution: | JIA Yan,GAO Bo(Department of Prosthodontics,College of Stomatology,Fourth Military Medical University,Xi'an 710032,China) |
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| Abstract: | Objective To evaluate the biological safety of a Ni-62.9Cr-23 alloy fabricated by laser solid forming technology.Methods According to the requirements of national standards GB/T16886-2003,YY/T0279-1995 and YY/T0244-1996,general cytotoxicity,acute systemic toxicity,hemolysis testing,oral mucous membrane irritation testing were used to evaluate the alloy.Results The alloy was indicated having no cytotoxicity and with a hemolytic rate of 0.385%.The oral mucous membrane irritation testing showed that the alloy ... |
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| Keywords: | laser solid forming Ni-Cr alloy biological safety dental materials |
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