| 板蓝根F022部位对内毒素致家兔发热模型的解热作用 |
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| 引用本文： | 林爱华,刘奕明,丘小惠,刘云海. 板蓝根F022部位对内毒素致家兔发热模型的解热作用[J]. 中药新药与临床药理, 2005, 16(6): 420-421 |
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| 作者姓名： | 林爱华 刘奕明 丘小惠 刘云海 |
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| 作者单位： | 1. 广州中医药大学附属广东省中医院,广州,510120
2. 华中科技大学同济医学院附属同济医院,武汉,430030 |
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| 摘 要： | 目的研究板蓝根F022部位对内毒素致热家兔的解热作用,筛选抗内毒素有效部位.方法通过半体内和体内实验,静脉给予内毒素后0.5,1,2,3,4 h,分别测量家兔体温.结果在半体内和体内实验中,F022均对内毒素致热家兔具有很好的解热作用.结论F022可作为板蓝根解热活性主体进行进一步研究.
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| 关 键 词： | 板蓝根 内毒素 解热 |
| 文章编号： | 1003-9783（2005）06-0420-02 |
| 收稿时间： | 2005-06-29 |
| 修稿时间： | 2005-06-29 |
Studies on Anti- pyretic Effect of F022 Components from Radix Isatidis on Rabbit Fever Models Induced by Endotoxin |
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| LIN Aihua,LIU Yiming,QIU Xiaohui,LIU Yunhai. Studies on Anti- pyretic Effect of F022 Components from Radix Isatidis on Rabbit Fever Models Induced by Endotoxin[J]. Traditional Chinese Drug Research & Clinical Pharmacology, 2005, 16(6): 420-421 |
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| Authors: | LIN Aihua LIU Yiming QIU Xiaohui LIU Yunhai |
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| Affiliation: | 1.Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou University ofTCM, Guangzhou 510120, China;2. Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China |
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| Abstract: | Objective To observe the anti-pyretie effect of F022 from Radix Isatidis. Methods The fever model was induced by intravenous injection of endotoxin into rabbits. Body temperature of the rabbits was measured at 0.5, 1, 2, 3, and 4h after administration in semi-vivo and in vivo. Results F022 subsided the fever in rabbits induced by endotoxin in semi-vivo and vivo. Conclusion It is valuable for further research that F022 component is used as the main to screen anti-pyretic active constituent. |
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| Keywords: | Radix lsatidis, Endotoxin Anti-pyretic |
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