Expression of four housekeeping proteins in elderly patients with schizophrenia |
| |
| Authors: | Deborah Elaine Bauer Vahram Haroutunian Robert E. McCullumsmith James H. Meador-Woodruff |
| |
| Affiliation: | (1) Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, SC560, 1530 3rd Ave S., Birmingham, AL 35294-0017, USA;(2) Program in Neuroscience, University of Michigan, Ann Arbor, MI, USA;(3) Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA |
| |
| Abstract: | We compared protein expression by Western blot analysis in four areas of postmortem brain from patients with schizophrenia and control subjects for several proteins that are often used as controls for Western blot studies: β-tubulin, actin, glyceraldehyde-3-phosphate dehydrogenase, and valosin-containing protein. We did not detect any differences in expression between subjects with schizophrenia and a comparison group. These results suggest that all four proteins are suitable loading controls for postmortem studies of schizophrenia. Supported by MH53327 (JMW), MH78378 (DEB), MH064673 & MH066392 (VH) and MH074016 (REM). |
| |
| Keywords: | VCP GAPDH Anterior cingulate cortex Dorsolateral prefrontal cortex Hippocampus Primary visual cortex |
| 本文献已被 SpringerLink 等数据库收录！ |
|
