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| Bcl-2在非小细胞肺癌中的表达与临床病理特征的关系 | |
| 引用本文： | 杨瑞,程哲,张楠.Bcl-2在非小细胞肺癌中的表达与临床病理特征的关系[J].医药论坛杂志,2006,27(4):8-9. |
| 作者姓名： | 杨瑞 程哲 张楠 |
| 作者单位： | 1. 河南省胸科医院,郑州市,450003 2. 郑州大学第一附属医院呼吸内科,郑州市,450052 3. 河南中医学院第一附属医院,郑州市,450003 |
| 摘 要： | 目的研究Bc l-2在人类非小细胞肺癌中的表达与临床病理特征的关系。方法应用免疫组织化学(S-P法)检测80例非小细胞肺癌组织标本和40例肺良性病变组织中Bc l-2的表达水平。结果非小细胞肺癌组织中Bc l-2表达水平(51.2%)显著高于肺良性病变组织(12.5%)(P<0.01);非小细胞肺癌组织中Bc l-2表达水平升高与肺癌组织学类型存在相关性(P<0.05)。结论Bc l-2表达升高与肺癌的发生、发展关系密切。 |
| 关 键 词： | 非小细胞肺癌 免疫组化 |
| 文章编号： | 1672-3422(2006)04-0008-02 |
| 收稿时间： | 01 8 2006 12:00AM |
| 修稿时间： | 2006年1月8日 |
The Relationship between the Expression of Bcl-2 and Clinical Pathology Characteristic |
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| YANG Rui,CHENG Zhe,ZHANG Nan.The Relationship between the Expression of Bcl-2 and Clinical Pathology Characteristic[J].Journal of Medical Forum,2006,27(4):8-9. | |
| Authors: | YANG Rui CHENG Zhe ZHANG Nan |
| Institution: | Henan Chest Hospital, Zhengzhou 450003, China |
| Abstract: | Objective To investigate the expression of Bcl-2 and the relationship between the expression and the clinical pathology characteristic in non-small cell lung cancer(NSCLC).Methods The expression of Bcl-2 was detected in 80 NSCLC samples and 40 lung benign lesion tissues as control by immunohistochemistry(S-P).Results The expression level of Bcl-2 was found to be significantly higher in NSCLC tissues than that in benign lesion tissues(P<0.01);The expression level of Bcl-2 was closely related to histological classification in lung cancer patients(P<(0.05)).Conclusion The increasing of Bcl-2 expression is may be related to the pathogenesis and development of lung cancer. |
| Keywords: | Bcl-2 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |