Prostate boundary detection and volume estimation using TRUS images for brachytherapy applications |
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Authors: | Vladimir Misic Varsha Sampath Yan Yu Eli Saber |
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Institution: | (1) Medical Physics Division, Thomas Jefferson University, Philadelphia, PA 19107, USA;(2) Electrical Engineering Department, Rochester Institute of Technology, Rochester, NY 14627, USA |
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Abstract: | Objective: Authors propose a semi-automatic segmentation algorithm for three-dimensional prostate boundary detection from trans-rectal
ultrasound images. As a part of brachytherapy treatment with seeds for early stage prostate cancer, a patient’s prostate is
scanned using a trans-rectal ultrasound probe, its boundary is manually outlined, and its volume is estimated for dosimetry
purposes. Proposed algorithm requires a reduced amount of radiologist’s input, and thus speeds up the surgical procedure.
Methods: The proposed segmentation algorithm utilizes texture differences between ultrasound images of the prostate and the surrounding
tissues. It is carried out in the polar coordinate system and uses three-dimensional data correlation to improve the smoothness
and reliability of the segmentation. The algorithm is applied to axial trans-rectal ultrasound images and the results are
compared to the “ground truth” set by manual prostate boundary outlining (by experienced radiologist). Method is validated
on six patients.
Results: In our tests, the proposed algorithm estimated prostate volume within 95% of the original radiologist’s estimate.
Conclusions: The boundary segmentation obtained from the algorithm can reduce manual input by a factor of 3, without significantly affecting
the accuracy of the segmentation. The reduction in the manual input reduces the overall brachytherapy procedure time. |
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Keywords: | Brachytherapy Three-dimensional texture segmentation Feature Extraction |
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