A patient undergoing chronic dialysis whose renal anemia was successfully corrected by treatment with cinacalcet |
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Authors: | Oshiro Yoshiyuki Tanaka Hisataka Okimoto Niro |
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Institution: | (1) Division of Nephrology, Department Internal Medicine, Kawasaki Medical School Kawasaki Hospital, 2-1-80 Nakasange, Kitaku, Okayama Okayama, 700-8505, Japan;(2) Department of General Internal Medicine 1, Kawasaki Medical School, Okayama, Japan |
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Abstract: | A 62-year-old female dialysis patient with chronic glomerulonephritis had been receiving hemodialysis therapy for 32 years.
In 1985 she underwent a parathyroidectomy for secondary hyperparathyroidism (HPT); however, her parathyroid hormone (PTH)
levels gradually increased. Her serum calcium level ranged from 9.0 to 10.0 mg/dL, which caused difficulties in performing
vitamin D injection therapy. No parathyroid glands were seen by echography or scintigraphy. On 31 March 2008 her intact PTH
(iPTH) level was 895 pg/mL so treatment with cinacalcet 25 mg/day was started. After 3 months her iPTH level decreased to
269 pg/mL and her hemoglobin level increased from 9.3 to 12.9 g/dL. In some cases of severe HPT, anemia improves after parathyroidectomy;
however, in this case, cinacalcet improved not only secondary HPT but also anemia. |
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Keywords: | |
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