磁敏感加权成像突出血管征显著程度的影响因素的探究

目的探讨影响超急性期/急性期的缺血性卒中患者的突出血管征(prominent vessel sign,PVS)显著程度的相关临床与影像因素,了解PVS对超急性期/急性期卒中的临床意义。方法纳入超急性/急性期卒中患者128例,记录患者性别、年龄、深穿支、起病到首次MRI扫描时间、高血脂、卒中史、糖尿病史、高血压、近期吸烟史、既往吸烟史、短暂性脑缺血发作、入院前NIHSS评分、梗阻程度、梗阻部位。分类资料的组间比较采用χ^2检验,计量资料组间比较采用Kruskal-Wallis H检验;χ^2Fisher确切概率法比较PVS等级与梗阻程度、梗阻部位、起病至扫描时间之间的关系。结果PVS的显著程度在性别、年龄、起病-拟首次MRI扫描时间、高血脂、卒中史、糖尿病史、高血压、近期吸烟、既往吸烟、短暂性脑缺血发作方面的差异均无统计学意义(P>0.05),在深穿支梗死和入院前NIHSS评分方面差异有统计学意义(P<0.05)。PVS显著程度与梗阻程度和梗阻部位分级相关,且呈线性相关。结论PVS对大血管梗阻部位较近、梗阻程度较重和临床症状较重的缺血性卒中患者更有临床意义。

Study of Investigating the Influence Factors of Prominence Grading of Prominent Vessel Sign on Susceptibility Weighted Imaging

Objective To explore the clinical and imaging factors that affect the significance of prominent vessel sign PVS in patients with ischemic stroke in the hyper-acute phase/acute phase,and to understand the clinical significance of PVS for stroke in the hyperacute/acute phase.Methods A total of 128 hyperacute/acute stroke patients were enrolled,and their gender,age,deep perforating branch,time from onset to first MRI scan,hyperlipidemia,stroke history,diabetes history,hypertension,recent smoking history,previous smoking history,TIA,NIHSS score before admission,degree of obstruction,and location of obstruction were analyzed.Theχ^2 test was used to compare the classified data,and the Kruskal-Wallis H test was used to compare the measurement data.Theχ^2 Fisher exact probability method was used to compare the relationship between the PVS level and the degree of obstruction,the location of the obstruction,and the onset to scan time.Results There were no significant differences in PVS in terms of gender,age,and onset-to-first MR scan time,and hyperlipidemia,history of stroke,history of diabetes,hypertension,recent smoking,previous smoking,TIA,and other aspects(P>0.05).There were statistically significant differences in deep perforating branch infarction and pre-hospital NIHSS scores(P<0.05).The significant degree of PVS is related to the degree of obstruction and the grade of obstruction site,and the relation is linear.Conclusion PVS is more clinically significant for patients with ischemic stroke who have a close site of large vessel obstruction,severe obstruction,and severe clinical symptoms.