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Treatment effect analysis of curettage for jaw cysts based on volumetric assessment and image registration
Affiliation:1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral and Maxillofacial Surgery, West China School & Hospital of Stomatology, Sichuan University, No. 14, 3rd Section of Renmin South Road, Chengdu, 610041, China;2. Stomatological Hospital of Chongqing Medical University, Chongqing, 401147, China;3. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral Radiology, West China School & Hospital of Stomatology, Sichuan University, No. 14, 3rd Section of Renmin South Road, Chengdu, 610041, China;1. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, PR China;2. Department of Stomatology, Changhai Hospital, Shanghai, 200433, PR China;1. Department for Oral and Cranio-Maxillo and Facial Plastic Surgery, University of Cologne, Germany, Head of Department: Prof. Dr. Dr. Joachim E. Zöller;2. Department of Anaesthesiology and Intensive Care Medicine (Head: Prof. Dr. Bernd W. Böttiger), University Hospital of Cologne, Faculty of Medicine and University Hospital of Cologne, Germany;1. Universityclinic of Bonn, Department of Oral, Cranio-Maxillo and Facial Plastic Surgery, Venusberg Campus 1, 53127, Bonn, Germany;2. University of Bonn, Faculty of Medicine, Department of Medical Biometry, Informatics and Epidemiology Venusberg Campus 1, 53127, Bonn, Germany;1. Department of Regenerative Oral Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8588 Japan;2. Department of Orthodontics and Dentofacial Orthopedics, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8588 Japan;3. Department of Oral Surgery, Imakiire General Hospital, 43-25 Korai-Cho, Kagoshima, 890-0051 Japan
Abstract:The study was conducted to develop a visual and intuitive quantitative evaluation method for maxillary cystic lesions after curettage. Mimics 16.0 and Geomagic Studio 2013 were used to form a precise reconstruction of the cystic lesion morphology of 60 cases; the average reduction rates and 95% confidence interval were calculated. Computed tomography (CT) registration was performed before and after surgery to observe morphology features of the bone regeneration of the cystic area. The average reduction rates (RR) of the cysts after curettage were (43.56 ± 16.79)%, (54.33 ± 17.15)% and (68.53 ± 15.99)% at 3 months, 6 months and 12 months after surgery, respectively. The average monthly reduction rates (MRR) were (12.07 ± 4.35)%, (8.16 ± 2.84)% and (5.35 ± 1.52)% at 3 months, 6 months and 12 months after surgery, respectively. Correlation analysis by comparing with each group showed that the effect of sex and age in the 3-month group and the initial size in the 12-month group on RR and MRR were statistically significant. Within the limitations of the study it seems that the chosen approach for quantitative evaluation of the therapeutic effect of curettage for jaw cystic lesions might facilitate visual and quantitative follow-up of cyst curettage and timely detection of recurrence.
Keywords:Cystic lesions  Curettage  Evaluation of curative effect  Registration analysis  Three-dimensional reconstruction
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