国家标准化代谢性疾病管理宁波分中心2型糖尿病患者的血糖管理效果

目的 比较宁波地区国家标准化代谢性疾病管理中心（National Metabolic Management Center, MMC）和常规住院模式对2型糖尿病患者的血糖管理效果。方法 入选2018年3月至2020年1月在宁波市第一医院门诊就诊并纳入MMC管理的367例 2型糖尿病患者为MMC组。按照年龄、性别、病程、基线的空腹血糖及糖化血红蛋白水平以1∶1匹配原则选取2018年3月至2020年1月在宁波市第一医院住院治疗的2型糖尿病患者为住院组。MMC组按照MMC标准对糖尿病患者进行诊疗,住院组采取三甲医院的常规住院诊疗模式。回顾性分析随访半年后两种管理模式对患者血糖水平的影响。结果 随访半年后,MMC诊疗模式组和住院诊疗模式组管理前后空腹血糖、糖化血红蛋白、总胆固醇、甘油三酯、低密度脂蛋白胆固醇、丙氨酸转氨酶均较基线水平明显改善（P＜0.05）。 结论 MMC对宁波地区2型糖尿病患者的糖化血红蛋白水平有较大改善作用,从8.32%下降至6.91%。与住院组相比,MMC组能够达到同等的血糖控制水平。

Effect of Ningbo Branch Center of the National Metabolic Management Center on blood glucose management in patients with type 2 diabetes mellitus

Objective To compare the effects of glycemic management between the National Metabolic Management Center (MMC) and routine hospitalization on patients with type 2 diabetes mellitus(T2DM). Methods Totally 367 patients with T2DM who were involved in the management of MMC and treated in Ningbo First Hospital's clinic from March, 2018 to January, 2020, were selected as MMC group. The hospitalized patients with T2DM) in Ningbo First Hospital were selected as hospitalization group from March, 2018 to January, 2020 according to 1∶1 matching principle based on age, gender, course, fasting blood grulose's basal level and hemoglobin A1c's basal level. Patients in MMC group were treated according to MMC standards, while those in hospitalization group had routine treatment of three A hospitals. After the follow up of half a year, the effects of two kinds of management on patients glycemic level were analyzed retrospectively.Results After the follow up of half a year, compared with the baseline, fasting blood glucose, hemoglobin A1c, total cholesterol, triglyceride, low density lipoprotein cholesterol, alanine aminotransferase in both groups were significantly improved (P<0.05). Conclusion MMC has good effects on the improvement of hemoglobin A1c level which decreased from 8.32% to 6.91% in the patients. Compared with the hospitalization group, MMC group can reach the same level of glucose control.