荞麦化学成分对2型糖尿病患者相关并发症的预防

目的 探讨荞麦化学成分对2型糖尿病患者相关并发症的预防效果。方法 选取确诊的2型糖尿病患者102例。将患者分为观察组及对照组。根据糖尿病膳食标准定量摄入，观察组使用荞麦粉作为主食，对照组使用小麦粉为主食。比较两组干预前后血糖、血压、血脂及抗氧化能力等情况。结果 干预后观察组收缩压、总胆固醇（TC）明显低于对照组（P＜0.05）；观察组高密度脂蛋白（HDL C）高于对照组（P＜0.05）；干预后观察组空腹血糖（FPG）、餐后2h血糖（2 hPG）、糖化血红蛋白（HbA1c）及丙二醇（MDA）均低于干预前及对照组（P＜0.05）；干预后观察组患者超氧化物歧化酶（SOD）活性显著高于对照组及干预前（P＜0.05）。结论 荞麦可能通过改善患者血糖水平、血脂血压情况及降低MDA含量、升高SOD活性预防2型糖尿病患者并发症的发生。

Preventive effect of buckwheat chemical composition on related complications of type 2 diabetes mellitus

Objective To get an insight into the preventive effect of buckwheat chemical composition on related complications in patients with type 2 diabetes mellitus. Methods A total of 102 patients with confirmed type 2 diabetes were selected. The patients were divided into observation group and control group. According to the standard dietary intake of diabetes, patients in observation group used buckwheat flour as the staple food, and patients in control group used wheat flour as the staple food. Blood glucose, blood pressure, blood lipids and antioxidant capacity were compared before and after intervention in two groups. Results After intervention, systolic blood pressure and total cholesterol (TC) in observation group were significantly lower than those in control group (P<0.05). After intervention, high density lipoprotein (HDL C) in observation group was higher than that in control group (P<0.05). Fasting blood glucose (FPG), 2 h postprandial blood glucose (2 hPG), glycosylated hemoglobin (HbA1c) and propylene glycol (MDA) in observation group were all lower than those before intervention and control group (P<0.05). The activity of superoxide dismutase (SOD) in observation group after intervention was significantly higher than that in control group and before intervention (P<0.05).Conclusion Buckwheat may prevent the complications of type 2 diabetes mellitus by improving the blood glucose level, blood lipid and blood pressure, reducing MDA content and increasing SOD activity.