| 异搏定和三苯氧胺合并化疗治疗42例恶性肿瘤观察 |
| |
| 引用本文： | 朱志真,张元雪. 异搏定和三苯氧胺合并化疗治疗42例恶性肿瘤观察[J]. 华夏医学, 1999, 0(2) |
| |
| 作者姓名： | 朱志真 张元雪 |
| |
| 作者单位： | 临沂市肿瘤医院 |
| |
| 摘 要： | 目的：探索异搏定和三苯氧胺作为耐药调变剂与化疗联合应用治疗恶性肿瘤的作用。方法：对８２例恶性肿瘤患者进行随机分组对照实验，４２例化疗同时加用异搏定和三苯氧胺，４０例单纯化疗，两组化疗方案相同。结果：两组总有效率分别为６１．９％和４０．０％，治疗组与对照组疗效相比有显著性差异（Ｐ＜０．０５），毒副作用两组无明显差别。结论：异搏定和三苯氧胺与化疗合用有助于改善化疗效果。
|
| 关 键 词： | 异搏定；三苯氧胺；化疗；耐药调变剂 |
Chemotherapy Combining with Verapamil and Tamoxifen for Malignant Tucmor TherapyObservations of Fortytwo Cases |
| |
| Zhu Zhizhen,Zhang YuanxueTumor Hospital of Linyi City,Linyi,Shandong Province. Chemotherapy Combining with Verapamil and Tamoxifen for Malignant Tucmor TherapyObservations of Fortytwo Cases[J]. Acta Medicinae Sinica, 1999, 0(2) |
| |
| Authors: | Zhu Zhizhen Zhang YuanxueTumor Hospital of Linyi City Linyi Shandong Province |
| |
| Abstract: | Objective: To study the effects of verapamil and tamoxifen as drugresistance modifier in combination with chemotherapy.Method: Eightytwo patients with malignant tumor were randomly assigned into two groups.One group of 42 patients, serves as treatment group, received chemotherapy combining with verapamil and tamoxifen; other group of 40 cases received the same regimen of chemotherapy alone, as the control.Results: Total effective rate of the treatment group and the control group was 61.9% and 40.0%, respectively, with a significant difference.Conclusion: Verapamil and tamoxifen in combination with chemotherapy helps to improve the effectiveness of chemotherapy. |
| |
| Keywords: | chemotherapy verapamil tamoxifen drugresistance modifier |
| 本文献已被 CNKI 等数据库收录！ |
