左室射血分数与心脏大小的相关性分析

目的:探讨左室射血分数(LVEF)与心脏大小的关系。方法:选取2009-2011年温州医学院附属第二医院641例基础病因为扩张型心肌病、高血压性心脏病、冠状动脉粥样硬化性心脏病、老年退行性心脏病等心血管疾病患者,根据其心脏超声多普勒检查结果分为2组:LVEF正常组(≥50%)和下降组(<50%)。应用多普勒超声心动图检测LVEF、左室舒张末期内径(LVEDV)、左室收缩末期内径(LVESV)、左房内径(LAD)、右室内径(RVD)等指标,对比分析不同LVEF值患者心脏大小的情况。结果:LVEF下降组LVEDV、LVESV、LAD及RVD明显大于LVEF正常组,差异均有统计学意义(P<0.01)。LVEF与LVEDV、LVESV呈显著负相关(r=-0.726,P<0.01;r=-0.828,P<0.01)。结论:LVEF与LVEDV、LVESV呈显著负相关,随着LVEDV、LVESV的增大,LVEF不断减少。

Relativity analysis on left ventricular ejection fraction and heart size

Objective: To explore the relationship between left ventricular ejection fraction(LVEF) and heart size.Methods: The clinical datas of 641 patients with dilated cardiomyopathy,hypertensive heart disease,coronary heart disease,or degenerative heart disease who were admitted to the Second Affiliated Hospital of Wenzhou Medical College from 2009 to 2011 were retrospectively analysed.These patients were divided into two groups by LVEF(normal LVEF:≥50% and degraded LVEF:<50%).Various physiological indexes such as LVEF,left ven-tricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left atrial diameter(LAD) and right ventricular diameter(RVD) were tested with Doppler echocardiography.Results: The values of LVEDV,LVESV,LAD and RVD of degraded LVEF group were higher than those of the group with normal LVEF,and the differences had statistical significance(P <0.01).There were all significantly negative correlations between LVEF and LVEDV,LVESV(r=-0.726,P <0.01;r=-0.828,P <0.01).Conclusion: There are significantly negative correlations between LVEF and LVEDV and LVESV,and with the enlargement of LVEDV and LVESV,the numerical value of LVEF continues to decrease.