| 去卵巢对大鼠睑板腺上皮细胞超微结构的影响 |
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| 引用本文： | 韦立顺,关华,杨以会,李联祥,张宇新. 去卵巢对大鼠睑板腺上皮细胞超微结构的影响[J]. 实用医学杂志, 2010, 26(4). DOI: 10.3969/j.issn.1006-5725.2010.04.023 |
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| 作者姓名： | 韦立顺 关华 杨以会 李联祥 张宇新 |
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| 作者单位： | 1. 河北工程大学医学院,河北省邯郸市,056002
2. 华北煤炭医学院,河北省唐山市,063002 |
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| 摘 要： | 目的:观察去卵巢后对大鼠睑板腺腺泡上皮超微结构的影响.方法:选择72只雌性青春期SD大鼠,随机分为手术组、假手术组和正常组.分别在2、4、6、8周检测血清雌二醇浓度,并随机取24只大鼠上睑板组织做透射电镜观察.结果:手术组术后4～8周血清雌二醇的浓度显著低于正常组和假手术组(P＜0.05).手术组术后4～8周,睑板腺腺泡上皮的基底细胞、过渡细胞损伤显著.结论:去卵巢后睑板腺腺泡上皮超微结构有明显的病理学改变.
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| 关 键 词： | 卵巢切除术 大鼠 睑板腺 超微结构 睑板腺功能障碍 |
Effect on epithelial ultrastructure of meibomian gland in ovariectomized rats |
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| WEI Li-shun,GUAN Hua,YANG Yi-hui,LI Lian-xiang,ZHANG Yu-xin. Effect on epithelial ultrastructure of meibomian gland in ovariectomized rats[J]. The Journal of Practical Medicine, 2010, 26(4). DOI: 10.3969/j.issn.1006-5725.2010.04.023 |
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| Authors: | WEI Li-shun GUAN Hua YANG Yi-hui LI Lian-xiang ZHANG Yu-xin |
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| Affiliation: | WEI Li-shun,GUAN Hua,YANG Yi-hui,LI Lian-xiang,ZHANG Yu-xin. Department of Anatomy,The Medical College of Hebei Engineering University,H,an 056002,China |
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| Abstract: | Objective To observe the effect on epithelial ultrastructure of meibomian gland acinus in ovariectomy rats. Methods Seventy-two adolescent female SD rats were selected and randomly divided into operated group,sham-operated group and normal group. Serum levels of estradiol were detected by radioimmunoassay on 2 weeks,4 weeks,6weeks,8weeks,respectively,and upper meibomian tissues in randomized 24 rats were observed by electron microscopy. Results Compared with normal group and sham-operated group,serum levels... |
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| Keywords: | Ovariectomy Rat Meibomian gland Ultrastructure Meibomian gland dysfunction |
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