Neuroleukemiosis: case report of leukemic nerve infiltration in acute lymphoblastic leukemia |
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Authors: | Aregawi Dawit G Sherman Jonathan H Douvas Michael G Burns Ted M Schiff David |
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Affiliation: | Department of Neurology, University of Virginia, Charlottesville, Virginia, USA. |
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Abstract: | We describe a patient in remission from acute lymphoblastic leukemia who developed a painless common peroneal neuropathy. Magnetic resonance imaging (MRI) revealed nerve thickening and enhancement, while a positron emission tomography (PET) scan demonstrated increased fluorodeoxyglucose uptake in a large segment of the neurovascular bundle, suggesting peripheral nerve infiltration. Both findings resolved following treatment with chemotherapy that crossed the blood-nerve barrier. In selected patients presenting with peripheral neuropathy, MRI and PET scan can be helpful in the diagnosis of peripheral nerve infiltration. |
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Keywords: | neurolymphomatosis leukemia peripheral nerve PET |
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