84例青年脑梗死患者病因特点的探讨

目的：探讨青年脑梗死常见病因。方法整群选取2011年1月—2015年12月该院神经内科收治青年脑梗死患者共84例，对其进行TOAST分型，对可控危险因素：如吸烟、高血压、血脂异常、高血糖、高同型半胱氨酸等情况进行分析，并随机抽取同期该院体检中心年龄相仿的患者85例患者进行对照，分析青年脑梗死患者的以上指标，得出结论。结果青年脑梗死发病率占同期全年龄组脑梗死患者的6.8%；其中男性占69.0%,女性占31.0%；18~34岁组占14.3%,35~45岁组占85.7%；不同TOAST分型患者所占的比例由高到低为：LAC 28例(33.3%),ATR 22例(26.2%), CEMB 15例(17.9%), OTH 13例(15.5%), UND 6例(7.1%)；青年卒中患者高血压、血脂异常、心脏病、糖尿病、吸烟、酗酒、高同型半胱氨血症的概率均显著高于正常对照组（P<0.05）。结论青年脑梗死病因复杂，小动脉闭塞型、大动脉粥样硬化型青年脑梗死患者为最常见的TOAST分型；高血压、血脂异常、心脏病、糖尿病、吸烟、酗酒、高同型半胱氨血症可能是青年缺血性卒中的重要危险因素。

84 Cases of Young Patients with Cerebral Infarction of the Cause and Char-acteristics of the Observation

Objective To investigate the common causes of cerebral infarction in young adults. Methods Group selection January 2011 to December 2015 in patients with cerebral infarction in young adults who were admitted to our hospital a to-tal of 84 patients, the by toast typing, of controllable risk factors, such as smoking, hypertension, dyslipidemia, hyper-glycemia, high homocysteine, situation analysis, and randomly selected the same period in our hospital medical center, simi-lar to the age of the patients with 85 cases of patients were compared. Analysis the above indicators in young patients with cerebral infarction, draws the conclusion. Results The youth cerebral infarction incidence accounted for 6.8%over the same period in all age groups of patients with cerebral infarction;men accounted for 69.0%, 31.0%of women;18 to 34 age group accounted for 14.3%, 35 ~ 45 years old group was 85.7%; different toast subtypes of patients accounted for the proportion of from high to low is:Lac 28 cases (33.3%), ATR in 22 cases (26.2%), cemb in 15 cases (17.9%), oth in 13 cases (15.5%), und in 6 cases (7.1%);young stroke patients with hypertension, dyslipidemia, heart disease, diabetes, smoking, drinking, the probability of homocysteine half cystine blood were significantly higher than those of normal control group (P< 0.05). Con-clusion The etiology of cerebral infarction in young complex, small artery occlusion, large artery atherosclerosis in young patients with cerebral infarction is the most common TOAST classification; hypertension, dyslipidemia, heart disease, dia-betes, smoking, drinking, homocysteine half cystine acidemia may is an important risk factor for ischemic stroke in young adults.