万州区宫颈癌危险因素病例对照研究

目的：探讨万州区妇女宫颈癌发病危险因素,为该地区宫颈癌有针对性的早期防治提供科学依据。方法随机选取以2011年1月-2015年12月5年间年龄在30~65岁的96例万州区妇幼保健院确诊宫颈癌患者为病例组,随机抽取同期全区两癌筛查中同龄非宫颈癌妇女200名为对照组,对其个人习惯、月经史、婚育史、性行为史、妇科病史、肿瘤家族史以及HPV感染等进行调查分析,筛选该区妇女宫颈癌发病危险因素。结果经Logistic回归分析表明,多次人流、早孕、HPV感染、妇科病史、初潮年龄过早和吸烟都与宫颈癌的发生密切相关(P<0.05),OR 值分别为5.9、4.91、2.94、2.68、2.34、1.56。结论该区宫颈癌发病结构呈现年轻化趋势,要提高重视度。为宫颈上皮内瘤变(CIN)患者建立上级保健医院同社区卫生服务中心的个人档案双向反馈机制,提高对宫颈癌的早筛查、早发现、早治疗,从而有效防止宫颈癌的发生和提高患者5年生存率。

Wanzhou District Cervical Cancer Risk Factors Case-control Study

Objective To explore the risk factors of cervical cancer in Wanzhou District, and to provide scientific evidence for the early prevention and treatment of cervical cancer in the region. Methods Random selection from January 2011 to December 2015 five-year age 30~65 96 Wanzhou District Maternal and child health hospital diagnosed cervical cancer patients as a case group, randomly selected from the same region Two Cancer Screening age non cervical cancer in women, 200 as control, were used to investigate and analyze the personal habits, menstrual history, obstetrical history, sexual history, gynecological disease, tumor family history and HPV infection, screening the risk factors of cervical cancer in this area. Results Logistic regression analysis showed that, repeated abortion, early pregnancy, HPV infection, gynecological history, early age at menarche and smoking are and cervical cancer occurrence is closely related (P<0.05). The OR Value were 5.9 and 4.91, 2.94, 2.68, 2.34, 1.56. Conclusion The incidence of cervical cancer in this area is younger and younger, which should be improved. for cervical intraepithelial neoplasia (CIN) in patients with established superior care hospital with community health service center profile of two-way feedback mechanism to improve on cervical cancer early screening, early discovery, early treatment, so as to effectively prevent cervical cancer occurrence and improve the patient's 5 year survival rate.