不同剂量下右美托咪定对重症AECOPD患者谵妄的发生率影响的研究

目的：研究不同剂量下右美托咪定对重症AECOPD患者谵妄发生率的影响。方法整群选取沈阳市第五人民医院ICU 2015年6月—2016年2月期间收治的48例重症AECOPD患者作为研究对象。随机将48例患者平均分为研究1组，研究2组和研究3组。采用不同麻醉方案干预。观察并记录3组患者心率变化﹑谵妄发生率。结果研究2组心动过缓发生率明显高于研究1组和研究3组，差异具有统计学意义(P<0.05)；研究3组中发生谵妄为4例，发生率为25%，显著高于其他2组，差异有统计学意义(P<0.05)。结论右美托咪定对降低重症AECOPD患者谵妄发生率有确切价值，实验剂量下两组谵妄的发生无差别，具有优越的临床推广应用价值。

Effects of Different Doses of Dexmedetomidine on Incidence of Delirium in Patients with Severe AECOPD

Objective To study the influence of different doses of dexmedetomidine given delirium incidence of severe AE-COPD patients. Methods Group selection Shenyang Fifth People's Hospital ICU admitted from June 2015 to February 2016 period 48 cases of severe AECOPD patients as research subjects. The randomized study of 48 patients were divided into study group 1, group 2 and group 3 Make. different anesthesia program interventions. Observe and record heart rate three groups of patients, the incidence of delirium. Results The two groups were significantly higher than bradycardia Study Group 1 and Study Group 3, with statistical significance difference (P<0.05); 3 study group 4 cases of delirium, the rate was 25%, significantly higher than the other two groups was statistically significant (P<0.05). Conclusion Dexmedetomidine given to reduce the incidence of delirium in patients with severe AECOPD have the exact value of the experimental dose groups no difference in the incidence of delirium, with excellent clinical application value.