ST段抬高心肌梗死直接经皮冠脉介入治疗后心肌灌注不良的预测因素及替罗非班的保护作用

目的：探讨ST段抬高心肌梗死(STEMI）直接经皮冠脉介入(PCI)术后心肌灌注水平的影响因素。方法方便选取并回顾性分析2011年7月一2016年6月在该院行直接PCI治疗的300例STEMI患者的临床资料。采用非条件多因素logistic回归分析检验心肌灌注水平的独立影响因素。结果入院时血糖、梗死前心绞痛、静脉应用替罗非班、发病至球囊开通时间、血栓负荷是STEMI患者直接PCI术后心肌灌注水平的独立影响因素(OR=1.764、0.52、0.43、1.984、2.764,P<0.05）。结论 ST段抬高心肌梗死(STEMI）直接经皮冠脉介入(PCI)术后心肌灌注水平的影响因素较多,临床医师应引起注意。

Predictive Factors of Myocardial Perfusion in ST Segment Elevation My-ocardial Infarction Treated by Direct Percutaneous Coronary Intervention and Protective Effect of Non Class

Objective To investigate the influencing factors of myocardial perfusion in patients with ST segment elevation myocardial infarction (STEMI) after direct percutaneous coronary intervention(PCI).Methods Convenient retrospective analy-sis of clinical data of 300 patients with STEMI who were treated with direct PCI in our hospital from July 2011 to June 2016. Logistic regression analysis was used to examine the independent influencing factors of myocardial perfusion. Results The independent influencing factors of myocardial perfusion (OR=1.764、0.52、0.43、1.984、2.764,P<0.05) in patients with were directly PCI after admission, blood glucose, pre infarction angina, intravenous application of non class, onset to balloon time, and thrombus load were the independent factors of myocardial perfusion in patients with STEMI. Conclusion ST seg-ment elevation myocardial infarction (STEMI) direct percutaneous coronary intervention (PCI) myocardial perfusion level of the impact of more factors, clinicians should be paid attention to.