B型尿钠肽检测在感染性休克相关心功能不全中的应用价值分析

目的：探讨血浆B型尿钠肽检测在感染性休克相关心功能不全中的应用价值。方法方便选取2013年5月—2016年4月之间该院收治的90例感染性休克患者为观察组,另选取同时期该院收治的90例低血容量性休克患者为对照组,采用单克隆非均相免疫法,对所有患者于晨起空腹抽静脉血进行血浆B型尿钠肽水平检测,进行组间对比分析；统计观察组中出现心功能不全的患者人数并分析血浆B型尿钠肽水平与感染性休克患者发生心功能不全的关系。结果①观察组患者血浆B型尿钠肽水平显著高于对照组[(937.8±216.7)ng/L vs.(233.2±131.6)ng/L,(P<0.01)]；②90例观察组患者中,有78例出现心功能不全(86.7%),其余12例患者心功能正常(13.3%),心功能不全的观察组患者血浆B型尿钠肽水平为(994.6±357.1)ng/L,心功能正常的观察组患者血浆B型尿钠肽水平为(727.5±263.7)ng/L,前者血浆B型尿钠肽水平高于后者,差异具有统计学意义(t=2.4837,P<0.05)。结论感染性休克患者的血浆B型尿钠肽水平与发生心功能不全之间有着紧密的关系。

Analyze the Application Value of B-type Natriuretic Peptide in Septic Shock Associated Cardiac Dysfunction

Objective To explore the application vaule of plasma B-type natriuretic peptide (PBNP) in septic shock associ-ated cardiac dysfunction. Methods Convenient selection between May 2013 to April 2016 were selected in our hospital 90 cases of septic shock patients as the observation group, select the same period in our hospital 90 cases of hypovolemic shock patients as control group, using monoclonal heterogeneus immunoassay, detection of plasma B type natriuretic peptide levels in all patients in the morning fasting venous blood were compared between groups; the number of patients with heart failure and analysis of plasma B type natriuretic peptide levels in patients with septic shock occurred between heart failure occurred in the observation group statistics. Results ①The level of PBNP in observation group was (937.8±216.7)ng/L and in control group was (233.2±131.6)ng/L. The level of PBNP in observation group was higher than control group and the dif-ference was statistically significant (P<0.05). ②In observation group, there were 78 cases occurrence of heart failure (86.7%). And another in 12 cases, the heart function was normal (13.3%). The level of PBNP in heart failure cases was (994.6±357.1)ng/L and in normal heart function was (727.5±263.7)ng/L. The level of PBNP in the foemer was higher than the later and the difference was statistically significant(t=2.4837,P<0.05). Conclusion In septic shock patients, PBNP levels and cardiac dysfunction had been close related.