国际泌尿病理协会Gleason评分系统对前列腺癌分级的影响

目的：探讨2005年国家泌尿病理协会(ISUP)Gleason评分系统(GS)对前列腺癌分级的影响。方法方便选择在2007年12月-2015年12月进入医院进行治疗的经尿道切除的前列腺癌患者43例,并且使用ISUP版GS系统对以前按照1977年GS修订版评分对经尿道切除的前列腺癌重新评分,比较2个版本GS的差异。结果修订版中以 Gleason 3级为主的比例为55.7%,Gleason 3级为次要结构的比例为51.1%,以Gleason 4级为主的比例为34.9%,以Gleason 4级为次要结构的比例为37.2%。 ISUP版中以Gleason 3级为主的比例为46.4%,以Gleason 3级为次要结构的比例为46.4%,以Gleason 4级为主的比例为44.2%,以Gleason 4级为次要结构的比例为41.9%。结论ISUP版中Gleason 3级所占比例明显下降,Gleason 4级所占比例明显上升。

International Association of Urology Pathological Gleason score system's In-fluence on the Classification of Prostate Cancer

Objective To investigate the 2005 national urological association of pathology (ISUP) Gleason score (GS) impact on prostate cancer classification. Methods Convenient choice in December 2007 to December 2015 in hospital for treatment of 43 patients with transurethral resection of prostate cancer, and use the ISUP version of the GS system for revision accord-ing to the 1977 GS score before to re-mark, transurethral resection of prostate cancer, comparing the difference between the two versions of GS. Results In the revision is given priority to with Gleason 3 level, 55.7% Gleason 3 level was 51.1%, the proportion of secondary structure is given priority to with Gleason 4 level, 34.9% in Gleason 4 level is the proportion of the secondary structure is 37.2%. ISUP version is given priority to with Gleason 3 level, 46.4% in Gleason 3 level was 46.4%, the proportion of secondary structure is given priority to with Gleason 4 level, 44.2% in Gleason 4 level is the proportion of the secondary structure is 41.9%. Conclusion ISUP Gleason 3 level significantly lower proportion of edition, proportion of Gleason 4 level rises apparently.