Bhutani曲线在新生儿高胆红素血症治疗中的应用

目的：研究新生儿小时胆红素百分位列线图(Bhutani曲线)在新生儿高胆红素血症治疗中的运用价值。方法方便选择90例诊断为新生儿高胆红素血症的患儿为研究对象,选取时间为2015年1—12月,随机分为3组,持续光疗组、间歇光疗组及观察组,每组30例,比较治疗后的不同疗效。结果观察组在治疗后48 h及72 h胆红素值分别为(233.27±32.11)μmol/L、(183.27±32.11)μmol/L,低于间歇光疗组,观察组住院时间(5.23±0.73)d较间歇光疗组短(P﹤0.05),观察组总光疗时间(42.7±8.89)h,较持续光疗组短,且观察组不良反应总发生率6.7%,较持续光疗组明显更低(P﹤0.05)。结论运用新生儿小时胆红素百分位列线图(Bhutani曲线)来合理安排光疗效果显著。

Application of Bhutani Curve in the Treatment of Neonatal Hyperbilirubine-mia

Objective To assess the value of hour-specific transcutaneous bilirubin in the treatment of neonatal hyper-bilirubinemia. Methods Convenient selection 90 patients diagnosed as children with neonatal hyperbilirubinemia for the study were randomly divided into three groups, Select time from January to December 2015, continue phototherapy group, intermittent light therapy group and the observation group, 30 cases compare the efficacy of different treatment. Results Ob-servation group were 48 hours and 72 hours after treatment bilirubin (233.27±32.11)μmol/L,(183.27±32.11)μmol/L, lower than the intermittent light therapy group, the observation group hospitalization time of (5.23±0.73)d relatively short inter-mittent light therapy group (P<0.05), the observation group total phototherapy time(42.7±8.89) hours, more sustained short light therapy group, and the group observed adverse reactions The overall incidence of 6.7%, compared with continuous light therapy group was significantly lower (P<0.05).Conclusion The use of neonatal bilirubin percentile ranks hour chart (Bhutani curve) to arrange the light effect is remarkable.