脑梗死患者Hcy、UA水平与头颈血管动脉粥样硬化及狭窄的相关性研究

目的：探讨脑梗死患者同型半胱氨酸（Hcy）、血尿酸（UA）水平与头颈血管动脉粥样硬化及狭窄的相关性。方法：选取2013年1月-2014年1月本院收治的脑梗死患者200例，根据头颈部螺旋连续扫描检查结果，将其分为观察组120例（动脉粥样硬化患者）和对照组90例（无动脉粥样硬化患者）；再根据头颈血管动脉狭窄程度，将观察组患者分为三组：轻度狭窄组、中度狭窄组及重度狭窄组，每组各40例。比较各组血清Hcy、UA的水平。结果：与对照组相比，观察组的血清Hcy、UA水平均明显升高，差异均有统计学意义（P〈0.05）。与轻度狭窄组相比，中度狭窄组、重度狭窄组的血清Hcy、UA水平均明显升高，差异均有统计学意义（P〈0.05）；重度狭窄组高于中度狭窄组，差异均有统计学意义（P〈0.05）。结论：脑梗死患者血清Hcy、UA水平明显升高，并与头颈血管动脉粥样硬化及狭窄程度具有明显相关性。

The Correlation Research of the Levels of Hcy,UA and Vascular Atherosclerosis and Stenosis in Head and Neck for Patients with Cerebral Infarction

Objective：To study the correlation of the levels of the homocysteine（Hcy）,blood uric acid（UA） and vascular atherosclerosis and stenosis in head and neck for patients with cerebral infarction.Method：200 patients with cerebral infarction in our hospital from Jan 2013 to Jan 2014 were selected,and they were divided into the observation group and the control group,included the 120 cases of atherosclerosis and the 80 cases of no-atherosclerosis,according to the screw continuous scan in head and neck. The patients in the observation group were divided into the three groups（the mild stenosis group,the moderate stenosis group,the severe stenosis group,40 cases per group）by the vascular stenosis degree of head and neck. The serum Hcy and UA levels were compared in the all groups.Result：Compared with the no-atherosclerosis group,the serum Hcy,UA levels in the atherosclerosis group were significantly increased with statistical difference（P〈0.05）. Compared with the mild stenosis group,the serum Hcy,UA levels in the moderate and severe stenosis groups were obviously increased with statistical difference（P〈0.05）;compared with the moderate stenosis group, the severe stenosis groups were obviously increased with statistical difference（P〈0.05）.Conclusion：The levels of serum Hcy and UA are significantly increasing for patients with cerebral infarction,and has the obvious correlation with vascular atherosclerosis and stenosis in head and neck.